General Information of Disease (ID: DISQZRON)

Disease Name Coronavirus infection
Disease Class 1D92: Coronavirus infection
Definition
Virus diseases caused by the coronavirus genus. Some specifics include transmissible enteritis of turkeys (enteritis, transmissible, of turkeys); feline infectious peritonitis; and transmissible gastroenteritis of swine (gastroenteritis, transmissible, of swine).
Disease Hierarchy
DISEYYZZ: Coronaviridae infectious disease
DISEM33Q: Infectious disease
DISQZRON: Coronavirus infection
ICD Code
ICD-11
ICD-11: 1D92
ICD-10
ICD-10: B34.2
Expand ICD-11
'1D92
Expand ICD-10
'B34.2
Disease Identifiers
MONDO ID
MONDO_0005719
MESH ID
D018352
MedGen ID
61674
SNOMED CT ID
186747009

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
VRX496 DMIO4V5 Approved Antisense drug [1]
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This Disease is Treated as An Indication in 6 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
CX-4945 DMWE7B9 Phase 2 Small molecular drug [2]
D-3252 DMHGMTZ Phase 1 NA [3]
GLS-5300 DMF1DP3 Phase 1 NA [4]
REGN3048 DM0E3ZG Phase 1 Antibody [5]
REGN3051 DM7LIV2 Phase 1 Antibody [5]
VRC-SRSDNA015-00-VP DMI1262 Phase 1 NA [6]
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⏷ Show the Full List of 6 Drug(s)
This Disease is Treated as An Indication in 1 Patented Agent(s)
Drug Name Drug ID Highest Status Drug Type REF
PMID27998201-Compound-1 DM5QH4C Patented Small molecular drug [7]
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This Disease is Treated as An Indication in 1 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Aloxistatin DMGW07M Discontinued in Phase 3 Small molecular drug [8]
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This Disease is Treated as An Indication in 9 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
5-(N,N-hexamethylene)-amiloride DMC4IUQ Preclinical Small molecular drug [8]
DecRVKRCMK DMAUILH Preclinical Small molecular drug [8]
GRL001 DM19T2V Preclinical Small molecular drug [8]
GRL0617 DMX9AGF Preclinical Small molecular drug [8]
LJ001 DMROKKZ Preclinical Small molecular drug [8]
m337 DM7HUVB Preclinical Antibody [8]
MERS-27 DMVGIB4 Preclinical Antibody [8]
MERS-4 DMS6KT8 Preclinical Antibody [8]
PJ34 DMXO6YH Preclinical Small molecular drug [8]
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⏷ Show the Full List of 9 Drug(s)
This Disease is Treated as An Indication in 1 Preclinical Drugs
Drug Name Drug ID Highest Status Drug Type REF
SSYA10-001 DM0NPIO Preclinical Small molecular drug [8]
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This Disease is Treated as An Indication in 1 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
DW-941 DMUMA36 Investigative NA [9]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1 ClinicalTrials.gov (NCT00246610) Safety Of VIRACEPT 625mg Administered To HIV-Infected Women During Pregnancy. U.S. National Institutes of Health.
2 ClinicalTrials.gov (NCT04668209) Silmitasertib (CX-4945) in Patients With Severe Coronavirus Disease 2019 (COVID-19) (CX4945). U.S. National Institutes of Health.
3 Clinical pipeline report, company report or official report of Protein Sciences Corporation.
4 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5 ClinicalTrials.gov (NCT03301090) A Safety, Tolerability, Pharmacokinetics and Immunogenicity Trial of Co-administered MERS-CoV Antibodies REGN3048 and REGN3051. U.S. National Institutes of Health.
6 ClinicalTrials.gov (NCT00099463) Phase I Study of a Vaccine for Severe Acute Respiratory Syndrome (SARS). U.S. National Institutes of Health.
7 Cathepsin B and L inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2017 Jun;27(6):643-656.
8 Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 May;15(5):327-47.
9 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.