Details of Disease

Disease Name

Endotoxic shock

Disease Class

1G40-1G41: Sepsis

Disease Hierarchy

DIS01GPL: Grass pollen hypersensitivity

DISR13YN: Endotoxic shock

ICD-11

ICD-11: 1G41

ICD-10

ICD-10: R57.2

Expand ICD-11

'1G41

Expand ICD-10

'R57.2

Disease Identifiers

MESH ID

D012772

MedGen ID

19963

SNOMED CT ID

371769008

General Information of Disease (ID: DISR13YN)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
MPL-S	DMNDCFY	Phase 3	NA	[1]
STEBVax	DMFDRNJ	Phase 1	NA	[2]
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This Disease is Treated as An Indication in 1 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Edobacomab	DM1LFMH	Discontinued in Preregistration	Monoclonal antibody	[3]
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This Disease is Treated as An Indication in 1 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
TSS-HIG	DMU98M9	Investigative	NA	[4]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	ClinicalTrials.gov (NCT00699764) Safety of a Herpes Simplex Candidate Vaccine (gD2t) With MPL and Its Efficacy to Prevent Genital Herpes Disease. U.S. National Institutes of Health.
2	ClinicalTrials.gov (NCT00974935) Phase I STEBVax in Healthy Adults. U.S. National Institutes of Health.
3	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000506)
4	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.