Details of Disease

General Information of Disease (ID: DISR2T25)

Disease Name Aphthous stomatitis
Synonyms oral aphthous ulcer; canker sore; oral ulcer; aphtha; oral aphthae; aphthous ulceration
Definition
A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval, lasting for 7-14 days and healing without scarring.
Disease Hierarchy
DISS93V5: Oral mucositis
DISR2T25: Aphthous stomatitis
Disease Identifiers
MONDO ID
MONDO_0004845
MESH ID
D013281
UMLS CUI
C0038363
MedGen ID
20959
HPO ID
HP:0032154
SNOMED CT ID
110426005

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
CARD8 OTXXZYWU Definitive Biomarker [1]
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References

1 Periodic Fever with Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome Is Associated with a CARD8 Variant Unable To Bind the NLRP3 Inflammasome.J Immunol. 2017 Mar 1;198(5):2063-2069. doi: 10.4049/jimmunol.1600760. Epub 2017 Jan 30.