Details of Disease | DrugMAP

General Information of Disease (ID: DISRJKTS)

Disease Name	Lymphedema
Synonyms	lymphoedema; lymphatic edema; lymphatic oedema (morphologic abnormality); lymphatic oedema; lymphatic edema (morphologic abnormality)
Definition	Excess fluid collection in tissues, causing swelling. It is the result of obstruction of lymphatic vessels or lymph nodes.
Disease Hierarchy	DIS57XO9: Lymphatic disease DISRJKTS: Lymphedema
Disease Identifiers	MONDO ID MONDO_0019297 MESH ID D008209 UMLS CUI C0024236 MedGen ID 6155 HPO ID HP:0001004 SNOMED CT ID 234097001

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
FLT4	TTDCBX5	Strong	Genetic Variation	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
GATA2	OTBP2QQ2	moderate	Biomarker	[2]
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References

1	Molecular characterization of two novel VEGFR3 mutations in Japanese families with Milroy's disease.Pediatr Int. 2008 Feb;50(1):116-8. doi: 10.1111/j.1442-200X.2007.02505.x.
2	Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome).Nat Genet. 2011 Sep 4;43(10):929-31. doi: 10.1038/ng.923.