Details of Disease | DrugMAP

General Information of Disease (ID: DISS1E36)

Disease Name	Mucopolysaccharidosis type 2, attenuated form
Synonyms	mucopolysaccharidosis type IIB; mucopolysaccharidosis type 2, attenuated form; MPSIIB; MPS2B; mucopolysaccharidosis type II, attenuated form; mucopolysaccharidosis type 2B; Hunter syndrome type B; iduronate 2-sulfatase deficiency type B
Definition	Mucopolysaccharidosis type 2, attenuated form (MPS2att), the less severe form of MPS2, leads to a massive accumulation of glycosaminoglycans and a wide variety of symptoms including distinctive facies, short stature, cardiorespiratory and skeletal findings. It is differentiated from mucopolysaccharidosis type 2, severe form by the absence of cognitive decline.
Disease Hierarchy	DIS87GLG: Mucopolysaccharidosis II DISS1E36: Mucopolysaccharidosis type 2, attenuated form
Disease Identifiers	MONDO ID MONDO_0016316 UMLS CUI C5679815 MedGen ID 1826165 Orphanet ID 217093

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
IDS	DEL45C2	Supportive	X-linked	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
IDS	OTZO94EO	Supportive	X-linked	[1]
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References

1	Clinical Practice Guidelines for Rare Diseases: The Orphanet Database. PLoS One. 2017 Jan 18;12(1):e0170365. doi: 10.1371/journal.pone.0170365. eCollection 2017.