Details of Disease

Disease Name

Tobacco dependence

Disease Class

6C4A: Nicotine use disorder

Disease Hierarchy

DIS01GPL: Grass pollen hypersensitivity

DISS81EF: Tobacco dependence

ICD-11

ICD-11: 6C4A.2

ICD-10

ICD-10: F17.2

ICD-9

ICD-9: 305.1

Expand ICD-11

'6C4A.2

Expand ICD-10

'F17.2

Expand ICD-9

305.1

General Information of Disease (ID: DISS81EF)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Nicotine	DMWX5CO	Approved	Small molecular drug	[1]
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This Disease is Treated as An Indication in 6 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
CYTISINE	DMUF0BJ	Phase 3	Small molecular drug	[1]
JNJ-39393406	DMUOEKM	Phase 2	Small molecular drug	[1]
Nicotine-Q	DMDBLWS	Phase 2	NA	[2]
X-22	DM7C0FT	Phase 2	NA	[1]
ARD-1600	DM9JJKF	Phase 1	NA	[1]
SELA-070	DMA175Q	Phase 1	NA	[3]
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⏷ Show the Full List of 6 Drug(s)

This Disease is Treated as An Indication in 2 Discontinued Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Dianicline	DMX2SHT	Discontinued in Phase 3	Small molecular drug	[4]
GW 468816	DMQ92WF	Discontinued in Phase 2	Small molecular drug	[5]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	ClinicalTrials.gov (NCT00369616) Efficacy and Safety of Nicotine-Qbeta Vaccine in Smokers. U.S. National Institutes of Health.
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4	Emerging drugs for the treatment of tobacco dependence. Expert Opin Emerg Drugs. 2009 Mar;14(1):23-32.
5	Executive summary: nicotine addiction. Drugs Today (Barc). 2005 Jun;41(6):419-25.
6	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027143)