Details of Disease | DrugMAP

General Information of Disease (ID: DISSHCUW)

Disease Name	46,XY sex reversal 6
Synonyms	SRXY6; 46,XY Sex reversal, partial or complete, Map3K1-related; 46,XY gonadal dysgenesis, partial or complete, Map3K1-related; 46,XY SEX reversal 6; 46XY sex reversal 6; 46,XY Sex reversal type 6; 46,XY sex reversal 6
Disease Hierarchy	DISLF3LT: 46,XY complete gonadal dysgenesis DISMNH0C: 46,XY partial gonadal dysgenesis DISSHCUW: 46,XY sex reversal 6
Disease Identifiers	MONDO ID MONDO_0013410 UMLS CUI C3151064 OMIM ID 613762 MedGen ID 462414

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
MAP3K1	TTW8TJI	Limited	Genetic Variation	[1]
MAP3K1	TTQBCEJ	Definitive	Autosomal dominant	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
MAP3K1	OTS3FVTY	Definitive	Autosomal dominant	[1]
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References

1	Mutations in MAP3K1 cause 46,XY disorders of sex development and implicate a common signal transduction pathway in human testis determination. Am J Hum Genet. 2010 Dec 10;87(6):898-904. doi: 10.1016/j.ajhg.2010.11.003.