Details of Disease

General Information of Disease (ID: DISTDR2M)

Disease Name Malignant germ cell tumor
Synonyms
malignant tumour of germ cell; malignant tumor of germ cell; germ cell tumor, malignant; germ cell cancer; malignant germ cell neoplasm; malignant neoplasm of the germ cell; malignant tumour of the germ cell; malignant tumor of the germ cell; malignant neoplasm of germ cell; malignant germ cell tumor; cancer of germ cell
Definition A gonadal or extragonadal malignant neoplasm that arises from germ cells. Representative examples include embryonal carcinoma, yolk sac tumor, and seminoma.
Disease Hierarchy
DIS62070: Germ cell tumor
DISAT1Z9: Advanced cancer
DISTDR2M: Malignant germ cell tumor
Disease Identifiers
MONDO ID
MONDO_0006290
UMLS CUI
C4048549
MedGen ID
890580
SNOMED CT ID
713582000

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 2 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
TSPY1 OTPY57X4 Strong Biomarker [1]
TSPY3 OTQK3AKI Strong Biomarker [1]
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References

1 45,X/46,X,psu dic(Y) gonadal dysgenesis: influence of the two cell lines on the clinical phenotype, including gonadal histology.Sex Dev. 2013;7(6):282-8. doi: 10.1159/000356173. Epub 2013 Nov 13.