Details of Disease

General Information of Disease (ID: DISTN8X8)

Disease Name Hereditary renal cell carcinoma
Synonyms hereditary renal carcinoma; familial renal carcinoma; hereditary renal cell carcinoma (disease); hereditary renal cell carcinoma; hereditary renal cell cancer
Definition An instance of renal cell carcinoma (disease) that is caused by an inherited modification of the individual's genome.
Disease Hierarchy
DISQZ2X8: Renal cell carcinoma
DISWH728: Renal cell adenocarcinoma
DISNCQLA: Inherited kidney disorder
DISTN8X8: Hereditary renal cell carcinoma
Disease Identifiers
MONDO ID
MONDO_0003008
UMLS CUI
C2608055
MedGen ID
392857

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
RNF139 OT0PR1X5 Strong Biomarker [1]
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References

1 Growth suppression induced by the TRC8 hereditary kidney cancer gene is dependent upon JAB1/CSN5.Oncogene. 2005 May 12;24(21):3503-11. doi: 10.1038/sj.onc.1208509.