Details of Disease | DrugMAP

General Information of Disease (ID: DISUKJK8)

Disease Name	X-linked complicated spastic paraplegia type 1
Synonyms	SPG1
Definition	An X-linked form of L1 syndrome characterized by spastic paraplegia, mild to moderate intellectual disability, normal MRI of the brain.
Disease Hierarchy	DISHZGSA: X-linked recessive disease DISYPSZE: L1 syndrome DISUKJK8: X-linked complicated spastic paraplegia type 1
Disease Identifiers	MONDO ID MONDO_0017630 UMLS CUI C5779711 MedGen ID 1843445

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
L1CAM	TTC9D3K	Supportive	X-linked	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
L1CAM	OTNWAQ4Y	Supportive	X-linked	[1]
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References

1	L1 Syndrome. 2004 Apr 28 [updated 2021 Jan 7]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(?) [Internet]. Seattle (WA): University of Washington, Seattle; 1993C2024.