Details of Disease

General Information of Disease (ID: DISUW4CP)

• Disease Name: Placenta disorder
• Synonyms: disease, placental; diseases, placental; diseases, placenta; disease, placenta; placental diseases; disorders, placenta; placental disease; disorder, placenta; placenta disorders; placenta disease; placenta disease or disorder; placenta diseases; placenta disorder; disease of placenta; placental disorder; disease or disorder of placenta; disorder of placenta
• Definition: A disease involving the placenta.
• Disease Hierarchy:
  DISGV2SE: Uterine disorder
  DISWD40R: Disease
  DIS5V7J6: Pregnancy disorder
  DISUW4CP: Placenta disorder
• Disease Identifiers:
  MONDO ID: MONDO_0005917
  MESH ID: D010922
  UMLS CUI: C0032045
  MedGen ID: 10781
  SNOMED CT ID: 125586008

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 2 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
IGF2	TTE8WGO	Strong	Biomarker	[1]
PRSS8	TTT4N0Q	Definitive	Therapeutic	[2]

This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
GCM1	OT5CPAUT	moderate	Altered Expression	[3]
SPINT2	OTQV7BKQ	Definitive	Biomarker	[2]

References

• [1] Placental-specific IGF-II is a major modulator of placental and fetal growth.Nature. 2002 Jun 27;417(6892):945-8. doi: 10.1038/nature00819.
• [2] Functional analysis of a missense mutation in the serine protease inhibitor SPINT2 associated with congenital sodium diarrhea.PLoS One. 2014 Apr 10;9(4):e94267. doi: 10.1371/journal.pone.0094267. eCollection 2014.
• [3] Decreased placental GCM1 (glial cells missing) gene expression in pre-eclampsia.Placenta. 2004 May;25(5):413-21. doi: 10.1016/j.placenta.2003.10.014.