Details of Disease

General Information of Disease (ID: DISVEVSJ)

• Disease Name: Malignant pleural effusion
• Disease Class: 2D72: Metastatic pleura neoplasm
• Disease Hierarchy:
  DIS01GPL: Grass pollen hypersensitivity
  DISVEVSJ: Malignant pleural effusion
• ICD Code:
  ICD-11: ICD-11: 2D72
  ICD-10: ICD-10: C78.2
  ICD-9: ICD-9: 511.81
  Expand ICD-11: '2D72
  Expand ICD-10: 'C78.2
  Expand ICD-9: 511.81

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Catumaxomab	DMXA9KU	Approved	Monoclonal antibody	[1]

This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Aglatimagene besadenovec	DMACVU8	Phase 3	Gene therapy	[2]
ICasp9M28z T cell	DMY6V5T	Phase 1	CAR T Cell Therapy	[3]

Molecular Interaction Atlas (MIA) of This Disease

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7385).
• [2] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [3] ClinicalTrials.gov (NCT02414269) Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin