Details of Disease

General Information of Disease (ID: DISVJCA1)

Disease Name Perennial allergic rhinitis
Synonyms non-seasonal allergic rhinitis; perennial allergic rhinitis; nonseasonal allergic rhinitis
Disease Class CA08: Vasomotor/allergic rhinitis
Definition Allergic rhinitis caused by indoor allergens and lasting year round.
Disease Hierarchy
DIS3U9HN: Allergic rhinitis
DISVJCA1: Perennial allergic rhinitis
ICD Code
ICD-11
ICD-11: CA08.03
ICD-10
ICD-10: J30.3
Expand ICD-11
'CA08.03
Expand ICD-10
'J30.3
Expand ICD-9
204.0,472.0,477,995.3
Disease Identifiers
MONDO ID
MONDO_0024332
MESH ID
D012221
UMLS CUI
C0035457
MedGen ID
19783
SNOMED CT ID
446096008

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Methylprednisolone DM4BDON Approved Small molecular drug [1]
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This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Ramatroban DMB8UQ3 Phase 2/3 Small molecular drug [2]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 2 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ALB TTFNGC9 Strong Biomarker [3]
HRH1 TTTIBOJ Strong Biomarker [4]
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This Disease Is Related to 1 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
CCL24 OT9LGHV0 moderate Biomarker [5]
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References

1 Methylprednisolone FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1911).
3 Gamma-tocopherol attenuates ozone-induced exacerbation of allergic rhinosinusitis in rats.Toxicol Pathol. 2009 Jun;37(4):481-91. doi: 10.1177/0192623309335630. Epub 2009 Apr 23.
4 Localization and upregulation of the nasal histamine H1 receptor in perennial allergic rhinitis.Mediators Inflamm. 2012;2012:951316. doi: 10.1155/2012/951316. Epub 2012 Oct 23.
5 Effects of Fluticasone Furoate Nasal Spray on Parameters of Eosinophilic Inflammation in Patients With Nasal Polyposis and Perennial Allergic Rhinitis.Ann Otol Rhinol Laryngol. 2017 Aug;126(8):573-580. doi: 10.1177/0003489417713505. Epub 2017 Jun 6.