Details of Disease | DrugMAP

General Information of Disease (ID: DISVU8V0)

Disease Name	Glomerulopathy with fibronectin deposits 2
Synonyms	glomerular nephritis familial with fibronectin deposits; fibronectin glomerulopathy; GFND2; glomerular nephritis, familial, with fibronectin deposits; glomerulopathy with fibronectin deposits 2; glomerulopathy with fibronectin deposits type 2; fibronectin glomerulopathy caused by mutation in FN1; FN1 fibronectin glomerulopathy
Definition	Any fibronectin glomerulopathy in which the cause of the disease is a mutation in the FN1 gene.
Disease Hierarchy	DISKTESP: Fibronectin glomerulopathy DISVU8V0: Glomerulopathy with fibronectin deposits 2
Disease Identifiers	MONDO ID MONDO_0011165 UMLS CUI C1866075 OMIM ID 601894 MedGen ID 356149 SNOMED CT ID 722759007

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 2 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
FN1	TTPJ921	Strong	Autosomal dominant	[1]
FN1	TTPJ921	Strong	Biomarker	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
FN1	OTB5ZN4Q	Strong	Autosomal dominant	[1]
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References

1	Mutations in FN1 cause glomerulopathy with fibronectin deposits. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2538-43. doi: 10.1073/pnas.0707730105. Epub 2008 Feb 11.