Details of Disease | DrugMAP

General Information of Disease (ID: DISWZ7GY)

Disease Name	Machado-Joseph disease type 3
Synonyms	SCA3, Machado type; azorean disease, type iii; spinocerebellar ataxia type 3, Machado type
Definition	Machado-Joseph disease type 3 is a subtype of Machado-Joseph disease (SCA3/MJD) of milder severity characterized by late onset, slower progression, and peripheral amyotrophy.
Disease Hierarchy	DISQBQID: Spinocerebellar ataxia type 3 DISWZ7GY: Machado-Joseph disease type 3
Disease Identifiers	MONDO ID MONDO_0017176 MESH ID D017827 UMLS CUI C0751670 MedGen ID 155611 Orphanet ID 276244

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
ATXN3	TT6A17J	Supportive	Autosomal dominant	[1]
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This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ATXN3	OTJVVGKT	Supportive	Autosomal dominant	[1]
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References

1	Clinical Practice Guidelines for Rare Diseases: The Orphanet Database. PLoS One. 2017 Jan 18;12(1):e0170365. doi: 10.1371/journal.pone.0170365. eCollection 2017.