Details of Disease

General Information of Disease (ID: DISX9CEW)

Disease Name	Parasitic infection
Synonyms	disease, parasitic; infestation; parasite infestation; diseases, parasitic; parasitosis; parasitism; ectoparasitic disease; parasitemia; parasitic infection; disease caused by parasite; parasitic infectious disease; parasitic disease
Disease Class	1D0Y-1G2Z: Parasitic infection
Definition	A successful invasion of a host by an organism that uses the host for food and shelter.
Disease Hierarchy	DISEM33Q: Infectious disease DISX9CEW: Parasitic infection
ICD Code	ICD-11 ICD-11: 1D0Y-1G2Z ICD-10 ICD-10: B85-B89 Expand ICD-11 '1G2Z Expand ICD-10 'B82; 'B82.0; 'B82.9; 'B89
Disease Identifiers	MONDO ID MONDO_0005135 UMLS CUI C0747256 MedGen ID 196662

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 6 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Agrimophol	DM21S0J	Approved	Small molecular drug	[1]
Arteflene	DMDYCVM	Approved	Small molecular drug	[1]
Azanidazole	DMY2D4W	Approved	Small molecular drug	[1]
Diloxanide	DMOTQRI	Approved	Small molecular drug	[1]
Levamisole	DM5EN79	Approved	Small molecular drug	[1]
Santonin	DM01VUX	Approved	Small molecular drug	[1]
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⏷ Show the Full List of 6 Drug(s)

This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
RF1V	DM9EHWO	Phase 2	NA	[2]
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This Disease is Treated as An Indication in 1 Investigative Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
CGP-20376	DM6BCMA	Investigative	Small molecular drug	[3]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
IL15RA	TTGN89I	Strong	Biomarker	[4]
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This Disease Is Related to 6 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ATOH1	OTBZYG2R	Strong	Biomarker	[5]
CHORDC1	OT3W6F1U	Strong	Biomarker	[6]
COQ2	OTDAKEY4	Strong	Biomarker	[7]
IL9R	OTILCLXA	Strong	Altered Expression	[8]
LGALS14	OTOR23GX	Strong	Biomarker	[9]
SCO1	OTC45UGB	Strong	Biomarker	[10]
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⏷ Show the Full List of 6 DOT(s)

References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	CSC's dynport vaccine company initiates phase 2b clinical trial of plague vaccine for u.s. department of defense. CSC. October 06, 2010.
3	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
4	Molecular characterization and expression analysis of interleukin 15 (IL15) and interleukin-15 receptor subunit alpha (IL15R) in dojo loach (Misgurnus anguillicaudatus): Their salient roles during bacterial, parasitic and fungal infection.Mol Immunol. 2018 Nov;103:293-305. doi: 10.1016/j.molimm.2018.10.012. Epub 2018 Oct 18.
5	Sox4 Promotes Atoh1-Independent Intestinal Secretory Differentiation Toward Tuft and Enteroendocrine Fates.Gastroenterology. 2018 Nov;155(5):1508-1523.e10. doi: 10.1053/j.gastro.2018.07.023. Epub 2018 Jul 25.
6	Self-selection of plant bioactive compounds by sheep in response to challenge infection with Haemonchus contortus.Physiol Behav. 2018 Oct 1;194:302-310. doi: 10.1016/j.physbeh.2018.06.013. Epub 2018 Jun 12.
7	A four-antigen mixture for rapid assessment of Onchocerca volvulus infection.PLoS Negl Trop Dis. 2009;3(5):e438. doi: 10.1371/journal.pntd.0000438. Epub 2009 May 19.
8	Th9 lymphocytes and functions of interleukin 9 with the focus on IBD pathology.Adv Med Sci. 2018 Sep;63(2):278-284. doi: 10.1016/j.advms.2018.03.002. Epub 2018 Mar 20.
9	Proteomic identification of galectin-11 and 14 ligands from Haemonchus contortus.PeerJ. 2018 Mar 19;6:e4510. doi: 10.7717/peerj.4510. eCollection 2018.
10	Increased frequency of HLA-DR3 and complotype SCO1 in Mexican mestizo children with amoebic abscess of the liver.Parasite Immunol. 1996 Oct;18(10):491-8. doi: 10.1046/j.1365-3024.1996.d01-16.x.