Details of Disease

Disease Name

Acquired thrombocytopenia

secondary thrombocytopenia; acquired thrombocytopenia

Definition

An instance of thrombocytopenia that is acquired during the lifetime of the individual.

Disease Hierarchy

DISU61YW: Thrombocytopenia

DISXH01C: Acquired thrombocytopenia

Disease Identifiers

MONDO ID

MONDO_0001198

UMLS CUI

C0154301

MedGen ID

509570

SNOMED CT ID

154826009

General Information of Disease (ID: DISXH01C)

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)

This Disease is Treated as An Indication in 8 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Betamethasone	DMAHJEF	Approved	Small molecular drug	[1]
Cortisone Acetate	DMG8K57	Approved	Small molecular drug	[2]
Dexamethasone	DMMWZET	Approved	Small molecular drug	[3]
Hydrocortisone	DMGEMB7	Approved	Small molecular drug	[4]
Methylprednisolone	DM4BDON	Approved	Small molecular drug	[5]
Prednisolone	DMQ8FR2	Approved	Small molecular drug	[6]
Prednisone	DM2HG4X	Approved	Small molecular drug	[7]
Triamcinolone	DM98IXF	Approved	Small molecular drug	[8]
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⏷ Show the Full List of 8 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
KIR2DS2	TTV3CFI	Strong	Biomarker	[9]
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This Disease Is Related to 2 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ANKRD26	OT2ENKKV	Strong	Genetic Variation	[10]
CRYL1	OT0SJSJM	Strong	Genetic Variation	[11]
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References

1	Betamethasone FDA Label
2	Cortisone acetate FDA Label
3	Dexamethasone FDA Label
4	Hydrocortisone FDA Label
5	Methylprednisolone FDA Label
6	Prednisolone FDA Label
7	Prednisone FDA Label
8	Triamcinolone FDA Label
9	KIR2DS2 as predictor of thrombocytopenia secondary to pegylated interferon-alpha therapy.Pharmacogenomics J. 2017 Jul;17(4):360-365. doi: 10.1038/tpj.2016.19. Epub 2016 Mar 15.
10	Clinical and laboratory characteristics in congenital ANKRD26 mutation-associated thrombocytopenia: A detailed phenotypic study of a family.Platelets. 2016 Nov;27(7):712-715. doi: 10.3109/09537104.2016.1171305. Epub 2016 Apr 28.
11	Buffy coat-derived platelets cryopreserved using a new method: Results from a pivotal clinical trial on thrombocytopenic patients with acute leukaemia.Transfus Apher Sci. 2019 Dec;58(6):102666. doi: 10.1016/j.transci.2019.10.008. Epub 2019 Nov 5.