Details of Disease | DrugMAP

General Information of Disease (ID: DISXOG13)

Disease Name	Pustular psoriasis
Synonyms	Pustular psoriasis; pustular psoriasis
Disease Hierarchy	DIS59VMN: Psoriasis DISXOG13: Pustular psoriasis
Disease Identifiers	MONDO ID MONDO_0022205 UMLS CUI C0152081 MedGen ID 508876 SNOMED CT ID 200973000

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
IL1RL2	TTUS18T	Strong	Biomarker	[1]
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This Disease Is Related to 4 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
CARD14	OTADQHOV	moderate	Biomarker	[1]
AP1S3	OTPCMV24	Strong	Genetic Variation	[2]
IL1F10	OTJAASGC	Strong	Biomarker	[3]
IL36RN	OT5CO95A	Strong	Biomarker	[4]
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References

1	Autoinflammatory keratinization diseases: An emerging concept encompassing various inflammatory keratinization disorders of the skin.J Dermatol Sci. 2018 May;90(2):105-111. doi: 10.1016/j.jdermsci.2018.01.012. Epub 2018 Feb 1.
2	The genetic basis for most patients with pustular skin disease remains elusive.Br J Dermatol. 2018 Mar;178(3):740-748. doi: 10.1111/bjd.15867. Epub 2018 Jan 22.
3	Differential Expression of IL-36 Family Members and IL-38 by Immune and Nonimmune Cells in Patients with Active Inflammatory Bowel Disease.Biomed Res Int. 2018 Dec 10;2018:5140691. doi: 10.1155/2018/5140691. eCollection 2018.
4	Interleukin (IL)-8 and IL-36 but not IL-36Ra are related to acrosyringia in pustule formation associated with palmoplantar pustulosis.Clin Exp Dermatol. 2019 Jan;44(1):52-57. doi: 10.1111/ced.13689. Epub 2018 Jun 12.