Details of Disease

General Information of Disease (ID: DISYHNYB)

• Disease Name: Adolescent meningitis
• Synonyms: acute aseptic meningitis; aseptic meningitis
• Disease Class: 1D01: Infectious meningitis
• Definition: Inflammation of the membranes surrounding the brain and spinal cord without a bacterial pathogen.
• Disease Hierarchy:
  DISQABAA: Meningitis
  DISYHNYB: Adolescent meningitis
• ICD Code:
  ICD-11: ICD-11: 1D01.10
  ICD-10: ICD-10: G00-G03
  ICD-9: ICD-9: 320-322
  Expand ICD-9: 320321322
• Disease Identifiers:
  MONDO ID: MONDO_0006662
  MESH ID: D008582
  UMLS CUI: C0025290
  MedGen ID: 7534
  SNOMED CT ID: 301770000

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 1 Clinical Trial Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
PF-05212366	DM3EHBH	Phase 3	NA	[1]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 1 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
NR4A3	TTJQB49	Strong	Biomarker	[2]

This Disease Is Related to 4 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
CHN1	OTM196M3	Strong	Biomarker	[2]
CHAF1B	OTOMK4KH	Definitive	Biomarker	[3]
CNOT7	OTJBKCPI	Definitive	Biomarker	[3]
CNOT8	OT6CMCS0	Definitive	Biomarker	[3]

References

• [1] Clinical pipeline report, company report or official report of Pfizer.
• [2] Molecular characterization of a new human coxsackievirus B2 associated with severe hand-foot-mouth disease in Yunnan Province of China in 2012.Arch Virol. 2017 Jan;162(1):307-311. doi: 10.1007/s00705-016-3075-5. Epub 2016 Oct 1.
• [3] Antibody against chromatin assembly factor-1 is a novel autoantibody specifically recognized in systemic lupus erythematosus.Lupus. 2014 Sep;23(10):1031-41. doi: 10.1177/0961203314536245. Epub 2014 May 16.