Details of Disease

General Information of Disease (ID: DISZGSCJ)

Disease Name Alphavirus infectious disease
Synonyms Alphavirus disease or disorder; Alphavirus caused disease or disorder
Definition Virus diseases caused by members of the alphavirus genus of the family togaviridae.
Disease Hierarchy
:
DISEM33Q: Infectious disease
DISZGSCJ: Alphavirus infectious disease
Disease Identifiers
MONDO ID
MONDO_0005643
MESH ID
D018354
UMLS CUI
C0206752
MedGen ID
64650
SNOMED CT ID
4003003

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 7 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
BCAR3 OTPJ17M8 Strong Genetic Variation [1]
HMGN4 OTD7GPRL Strong Biomarker [2]
MAVS OTTQ0J64 Strong Biomarker [3]
OAS3 OT6E5FYS Strong Genetic Variation [4]
RTN2 OTTZ5FW0 Strong Genetic Variation [1]
TSPAN9 OT3DI3NH Strong Biomarker [5]
SH2D3A OTVJBSRC Definitive Biomarker [6]
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⏷ Show the Full List of 7 DOT(s)

References

1 Novel Mutations in nsP2 Abolish Chikungunya Virus-Induced Transcriptional Shutoff and Make the Virus Less Cytopathic without Affecting Its Replication Rates.J Virol. 2019 Feb 5;93(4):e02062-18. doi: 10.1128/JVI.02062-18. Print 2019 Feb 15.
2 The prophylactic and therapeutic activity of a broadly active ribonucleoside analog in a murine model of intranasal venezuelan equine encephalitis virus infection.Antiviral Res. 2019 Nov;171:104597. doi: 10.1016/j.antiviral.2019.104597. Epub 2019 Sep 5.
3 Emerging Alphaviruses Are Sensitive to Cellular States Induced by a Novel Small-Molecule Agonist of the STING Pathway.J Virol. 2018 Feb 26;92(6):e01913-17. doi: 10.1128/JVI.01913-17. Print 2018 Mar 15.
4 The large form of human 2',5'-Oligoadenylate Synthetase (OAS3) exerts antiviral effect against Chikungunya virus.Virology. 2009 Feb 5;384(1):216-22. doi: 10.1016/j.virol.2008.10.021. Epub 2008 Dec 3.
5 Role of TSPAN9 in Alphavirus Entry and Early Endosomes.J Virol. 2016 Apr 14;90(9):4289-97. doi: 10.1128/JVI.00018-16. Print 2016 May.
6 Inflammatory monocytes mediate control of acute alphavirus infection in mice.PLoS Pathog. 2017 Dec 15;13(12):e1006748. doi: 10.1371/journal.ppat.1006748. eCollection 2017 Dec.