Details of Drug-Metabolizing Enzyme (DME)
General Information of Drug-Metabolizing Enzyme (DME) (ID: DE7HL3C)
DME Name | Cytochrome P450 101D2 (cyp101) | ||||
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Synonyms | Cytochrome P450 family 101 subfamily D member 2; Cytochrome P450-cam D2, Cytochrome P450cam D2; P450 101D2; cyp101D2 | ||||
Gene Name | cyp101 | ||||
UniProt ID | |||||
INTEDE ID | |||||
EC Number | EC: 1.14.15.1 | ||||
Lineage | Species: Novosphingobium aromaticivorans | ||||
Tissue Distribution | Primarily distributed in human gut. | ||||
Sequence |
MATNFDEAVRAKVERPANVPEDRVYEIDMYALNGIEDGYHEAWKKVQHPGIPDLIWTPFT
GGHWIATNGDTVKEVYSDPTRFSSEVIFLPKEAGEKYQMVPTKMDPPEHTPYRKALDKGL NLAKIRKVEDKVREVASSLIDSFAARGECDFAAEYAELFPVHVFMALADLPLEDIPVLSE YARQMTRPEGNTPEEMATDLEAGNNGFYAYVDPIIRARVGGDGDDLITLMVNSEINGERI AHDKAQGLISLLLLGGLDTVVNFLSFFMIHLARHPELVAELRSDPLKLMRGAEEMFRRFP VVSEARMVAKDQEYKGVFLKRGDMILLPTALHGLDDAANPEPWKLDFSRRSISHSTFGGG PHRCAGMHLARMEVIVTLEEWLKRIPEFSFKEGETPIYHSGIVAAVENVPLVWPIAR |
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Function | This enzyme is a P-450 heme-thiolate protein, and it also acts on (-)-camphor and 1,2-campholide, forming 5-exo-hydroxy-1,2-campholide. | ||||
Molecular Interaction Atlas (MIA) of This DME
Molecular Interaction Atlas (MIA) | ||||||||||||||||||||||||||||
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1 Approved Drug(s) Metabolized by This DME
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