Details of the Drug Combination

General Information of Drug Combination (ID: DC73DIS)

Drug Combination Name

BIO-300 DFN-15

Indication

Disease Entry	Status	REF
Chronic myelogenous leukemia	Investigative	[1]

Component Drugs

BIO-300 DMJ7NVI

DFN-15 DM3BF9B

N.A.

High-throughput Screening Result

Testing Cell Line: K-562

Zero Interaction Potency (ZIP) Score: 6.77

Bliss Independence Score: 6.16

Loewe Additivity Score: 5.25

LHighest Single Agent (HSA) Score: 8.38

Test Results of This Drug Combination in Other Disease Systems

Indication	DrugCom ID	Cell Line	Status	REF
Lung adenocarcinoma	DC2TBK7	MDA-MB-231	Investigative	[5]
Prostate carcinoma	DCJHVZN	PC-3	Investigative	[5]
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References

1	CheMBL Affinity Phenotypic Cellular Interaction Assay ID: CHEMBL1125966
2	Clinical pipeline report, company report or official report of Humanetics.
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5	CheMBL Affinity Phenotypic Cellular Interaction Assay ID: CHEMBL1125976