Details of the Drug Combination

General Information of Drug Combination (ID: DCJHVZN)

Drug Combination Name

BIO-300 DFN-15

Indication

Disease Entry	Status	REF
Prostate carcinoma	Investigative	[1]

Component Drugs

BIO-300 DMJ7NVI

DFN-15 DM3BF9B

N.A.

High-throughput Screening Result

Testing Cell Line: PC-3

Zero Interaction Potency (ZIP) Score: 7.21

Bliss Independence Score: 7.99

Loewe Additivity Score: 5.2

LHighest Single Agent (HSA) Score: 11.18

Test Results of This Drug Combination in Other Disease Systems

Indication	DrugCom ID	Cell Line	Status	REF
Chronic myelogenous leukemia	DC73DIS	K-562	Investigative	[5]
Lung adenocarcinoma	DC2TBK7	MDA-MB-231	Investigative	[1]
------------------------------------------------------------------------------------

References

1	CheMBL Affinity Phenotypic Cellular Interaction Assay ID: CHEMBL1125976
2	Clinical pipeline report, company report or official report of Humanetics.
3	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
5	CheMBL Affinity Phenotypic Cellular Interaction Assay ID: CHEMBL1125966