Details of the Drug Combinations

General Information of This Drug (ID: DM2HU9I)

Drug Name
Triamterene   DM2HU9I
Synonyms
Ademin; Ademine; Amteren; Anjal; Dazid; Diarol; Dinazide; Diren; Ditak; Diucelpin; Diurene; Diutensat; Diuteren; Dyberzide; Dyren; Dyrenium; Dytac; Dytenzide; Esiteren; Hidiurese; Hydrene; Hypertorr; Isobar; Jatropur; Jenateren; Kalspare; Masuharmin; Nephral; Noridil; Noridyl; Pterofen; Pterophene; Renezide; Reviten; Taturil; Teriam; Teridin; Triamizide; Triampur; Triamteren; Triamterena; Triamterenum; Triamteril; Triamterine; Triamthiazid; Tricilone; Trispan; Triteren; Triurene; Trizid; Turfa; Uretren; Urocaudal; Goldshield Brand of Triamterene; Jorba Brand of Triamterene; Pter ophene; SmithKline Beecham Brand of Triamterene; TRIAMTERENE USP; Thiazid Wolff; Triamteril complex; Wellspring Brand of Triamterene; Fluss 40; SKF 8542; T 4143; Ademin(e); Apo-triazide; Dyrenium (TN); Pteridine deriv. 11; SALI-PUREN; SK&F 8542; SK-8542; Tri-Span; Triamterena [INN-Spanish]; Triamterenum [INN-Latin]; SK&F-8542; Triamterene (JP15/USP/INN); Triamterene [USAN:INN:BAN:JAN]; 2,4,7-Triamino-6-fenilpteridina; 2,4,7-Triamino-6-fenilpteridina [Italian]; 2,4,7-Triamino-6-phenylpteridine; 6-PHENYL-2,4,7-TRIAMINO PTERIDINE; 6-Phenyl-2,4,7-pteridinetriamine; 6-Phenyl-2,4,7-triaminopteridine; 6-phenylpteridine-2,4,7-triamine
Indication
Disease Entry ICD 11 Status REF
Congestive heart failure BD10 Approved [1]
Edema MG29 Approved [1]
Hypertension BA00-BA04 Approved [1]
High blood pressure BA00 Investigative [2]
Therapeutic Class
Diuretics
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

52 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
Acamprosate + Triamterene DCCU3QG Acamprosate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Amodiaquine + Triamterene DC4KVWH Amodiaquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Arfolitixorin + Triamterene DCYBTC5 Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Triamterene DCD65RT Atenolol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
BIO-300 + Triamterene DC9DBOO BIO-300 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Buspirone + Triamterene DC49OO4 Buspirone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Chlorzoxazone + Triamterene DC5O94R Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Cytarabine + Triamterene DC1CV7W Cytarabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dantrolene + Triamterene DCPHGIH Dantrolene Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Doxorubicin + Triamterene DCO6KBD Doxorubicin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Everolimus + Triamterene DCOR8JC Everolimus Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Gefitinib + Triamterene DCOSAYX Gefitinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
IT-141 + Triamterene DC2YCF6 IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Kanamycin + Triamterene DCP0VVJ Kanamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
L-165041 + Triamterene DCYAU4B L-165041 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Levamisole + Triamterene DCD5BA9 Levamisole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Linagliptin + Triamterene DCO1IIO Linagliptin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maraviroc + Triamterene DCREAJA Maraviroc Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Metyrosine + Triamterene DC38VCP Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Oseltamivir + Triamterene DCT2SRJ Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PHA-739358 + Triamterene DCHKQAN PHA-739358 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Tiagabine + Triamterene DCF8A05 Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Ribavirin-TP DCOGRL2 Ribavirin-TP Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + GYKI-52466 DCLTZJ0 GYKI-52466 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + PMID28460551-Compound-2 DCTM63M PMID28460551-Compound-2 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Triapine DCN1B8X Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Acitretin DC5559W Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Tranexamic acid DCR98T6 Tranexamic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Palonosetron DCPDYR3 Palonosetron Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Emetine DC9C6XI Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Doxapram DCPG99M Doxapram Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Docetaxel DC7UQDR Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Ginsenoside Rb1 DCJBGND Ginsenoside Rb1 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Phensuximide DCKGUTS Phensuximide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Niclosamide DC767H0 Niclosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + PF-02545920 DCTBKUE PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Diazoxide DC6WV5B Diazoxide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Imatinib DCB9FKY Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Probenecid DCE7KS7 Probenecid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Pramipexole DCUN0J6 Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Moricizine DC05R7K Moricizine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Dopamine DCON7IB Dopamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Trimethobenzamide DCURRQZ Trimethobenzamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Maprotiline DCYCKPA Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Oxyphenbutazone DCIFERO Oxyphenbutazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Teriflunomide DCHIJA7 Teriflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Mycophenolic acid DCQRM9C Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Mefloquine DCYQVY2 Mefloquine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Auranofin DCDR3D1 Auranofin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Triamterene + Cerivastatin DCZFWXB Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Trihexyphenidyl + Triamterene DCU7514 Trihexyphenidyl Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vinblastine + Triamterene DC0GH52 Vinblastine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
------------------------------------------------------------------------------------
⏷ Show the Full List of 52 DrugCom(s)

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4329).
2 Triamterene FDA Label
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.