Details of the Drug Combinations

General Information of This Drug (ID: DM3JFIH)

Drug Name
Vancomycin   DM3JFIH
Synonyms Vancomycin (oral, MRSA), AuricX; Vancomycin (oral/pill, MSRA); Vancomycin (oral/pill, MSRA), AuricX/SRI International
Indication
Disease Entry ICD 11 Status REF
Bacteremia 1A73 Approved [1]
Bacterial endocarditis N.A. Approved [1]
Clostridioides difficile infection 1A04 Approved [1]
Methicillin-resistant staphylococci infection 1A00-1A09 Approved [2]
Neonatal sepsis N.A. Approved [1]
Staphylococcal pneumonia N.A. Approved [1]
Staphylococcus aureus infection N.A. Approved [1]
MRSA infection 1D01.0Y Investigative [3]
Skin infection 1F28-1G0Z Investigative [1]
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Structure
3D MOL is unavailable 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

18 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Linezolid + Vancomycin DCL6AED Linezolid Complicated Skin and Structure Infection [4]
Vancomycin + Cefazolin DC5Y73O Cefazolin Thoracic Surgery [5]
Vancomycin + Ceftazidime DCA70P6 Ceftazidime Peritoneal Dialysis Associated Peritonitis [6]
Vancomycin + Moxifloxacin DCBU8D8 Moxifloxacin Peritoneal Dialysis Associated Peritonitis [6]
Vancomycin + Aztreonam DCSGHS2 Aztreonam Complicated Skin and Soft Tissue Infection [7]
Vancomycin + Teicoplanin DCTKWFZ Teicoplanin Skin Diseases, Infectious [8]
Clindamycin + Vancomycin DCFZ98T Clindamycin Pre-Diabetes [9]
Linezolid + Vancomycin DCAX3EB Linezolid Hip Prosthetic Joint Infection [10]
Vancomycin + Loperamide DCHTNFE Loperamide Clostridium Difficile Infection [11]
Vancomycin + Metronidazole DC69VWO Metronidazole Clostridium Difficile [12]
Vancomycin + Daptomycin DCIIXKY Daptomycin Bacteremia [13]
Vancomycin + Amikacin DC75W85 Amikacin Nosocomial Neonatal Sepsis [14]
Vancomycin + Aztreonam DCKU834 Aztreonam Complicated Skin and Soft Tissue Infection [15]
Vancomycin + Nafcillin DCY1Y0Y Nafcillin Acute Hematogenous Osteomyelitis [16]
Vancomycin + Ceftriaxone DCOPY0X Ceftriaxone Nephrolithiasis [17]
Vancomycin + Imipenem DCKTUWU Imipenem Cirrhosis [18]
Vancomycin + Tobramycin DCJKM5T Tobramycin Surgical Site Infection [19]
Vancomycin + Cefazolin DCQGT1X Cefazolin Surgical Site Infections [20]
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References

1 Vancomycin FDA Label
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
4 ClinicalTrials.gov (NCT01363271) Cost Study of Linezolid Versus Vancomycin Among Previously Hospitalized Patients
5 ClinicalTrials.gov (NCT02285140) Prevention of Infections in Cardiac Surgery
6 ClinicalTrials.gov (NCT02787057) Vancomycin Plus Moxifloxacin Versus Vancomycin Plus Ceftazidime for the Treatment of Peritoneal Dialysis (PD)-Related Peritonitis
7 ClinicalTrials.gov (NCT01499277) Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections
8 ClinicalTrials.gov (NCT00430937) Efficacy and Safety of Daptomycin Versus Vancomycin or Teicoplanin for Treatment of Complicated Skin and Soft Tissue Infections
9 ClinicalTrials.gov (NCT02730962) Interventional Bioremediation of Microbiota in Metabolic Syndrome
10 ClinicalTrials.gov (NCT01757236) Efficacy and Safety Study of Antibiotic Treatment to Treat Hip Prosthetic Joint Infection
11 ClinicalTrials.gov (NCT02686645) Fecal Microbiota Therapy for Recurrent Clostridium Difficile Infection
12 ClinicalTrials.gov (NCT02466698) Intestinal Lavage for the Treatment of Severe C. Difficile Infections
13 ClinicalTrials.gov (NCT02208063) A Phase 3 Telavancin Staphylococcus Aureus (S. Aureus) Bacteremia Trial
14 ClinicalTrials.gov (NCT01867138) Neonatal Suspected Sepsis Treated With Cefazolin or Vancomycin
15 ClinicalTrials.gov (NCT02202135) Evaluation of Ceftaroline Fosamil vs Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections.
16 ClinicalTrials.gov (NCT01922011) Safety and Efficacy Study of Daptomycin Compared to Active Comparator in Pediatric Participants With Acute Hematogenous Osteomyelitis (AHO) (MK-3009-006)
17 ClinicalTrials.gov (NCT02384200) A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])
18 ClinicalTrials.gov (NCT01820026) Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis
19 ClinicalTrials.gov (NCT03308253) Study for Antibiotic Impregnated Calcium Sulfate Beads as Prophylaxis for Surgical Site Infection
20 ClinicalTrials.gov (NCT03402945) Prevention of Infections in Cardiac Surgery (PICS) Prevena Study