Details of the Drug Combinations

General Information of This Drug (ID: DM3RWXL)

Drug Name

Resveratrol DM3RWXL

Synonyms

Resveratrol; Resvida; KUC104385N; R 5010; SRT 501; Cis-resveratrol; PREVENTION 8 (RESVERATROL); RM-1812; SRT-501; Trans-resveratrol; CU-01000001503-3; KSC-10-164; Resveratrol-3-sulfate; Trans-3,4',5-trihydroxystilbene; Trans-3,4′,5-Trihydroxystilbene; Trans-1,2-(3,4',5-Trihydroxydiphenyl)ethylene; (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol

Indication

Disease Entry	ICD 11	Status	REF
Giant cell arteritis	4A44.2	Phase 3	[1]
Rheumatoid arthritis	FA20	Phase 3	[1]
Systemic sclerosis	4A42	Phase 3	[1]
Colorectal cancer	2B91.Z	Discontinued in Phase 2	[2]
Middle East Respiratory Syndrome (MERS)	1D64	Preclinical	[3]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

1 Investigative Drug Combination(s) Consisting of This drug

Normalized Drug Combination Synergy Score

Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Resveratrol + Idarubicin	DCTMWZY	Idarubicin	Glioblastoma? (Cell Line: T98G)	[4]
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1 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Resveratrol + Losartan	DCN39RC	Losartan	Diabetic Nephropathy	[5]
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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
2	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018787)
3	Effective inhibition of MERS-CoV infection by resveratrol. BMC Infect Dis. 2017 Feb 13;17(1):144.
4	Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
5	ClinicalTrials.gov (NCT02704494) Resveratrol's Effects in Diabetic Nephropathy