Details of the Drug Combinations

General Information of This Drug (ID: DMCQBFT)

Drug Name
Parthenolide   DMCQBFT
Synonyms
parthenolide; 20554-84-1; (-)-Parthenolide; CHEBI:7939; Parthenolide, Tanacetum parthenium; 4,5-alpha-Epoxy-6-beta-hydroxygermacra-1(10),11(13)-dien-12-oic acid gamma-lactone; partenolide; C15H20O3; 29552-41-8; Prestwick2_000550; Prestwick3_000550; Epitope ID:115014; SCHEMBL8220; BSPBio_001308; BSPBio_000599; MLS002153872; CHEMBL465158; BPBio1_000659; SCHEMBL13367522; BCBcMAP01_000041; Parthenolide, > MolPort-008-268-168; MolPort-003-959-089; HMS1361B10; HMS3402B10; HMS1989B10; HMS1791B10; HMS1569N21; HMS2096N21
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

9 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
BIIB-021 + Parthenolide DCQLH1N BIIB-021 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
Daporinad + Parthenolide DCX99EW Daporinad Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
Parthenolide + THAPSIGARGIN DCB3GZR THAPSIGARGIN Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
Parthenolide + Mifepristone DCMLOJE Mifepristone Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
Parthenolide + AS602868 DCNZAEL AS602868 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
Parthenolide + Tamoxifen DCK0UD6 Tamoxifen Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
Parthenolide + Ciclopirox DCKFK9F Ciclopirox Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
Parthenolide + Mefloquine DCBPDHS Mefloquine Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
RTB101 + Parthenolide DCN7VTJ RTB101 Diffuse intrinsic pontine glioma (Cell Line: SU-DIPG-XIII) [1]
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⏷ Show the Full List of 9 DrugCom(s)

References

1 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.