Details of the Drug

General Information of Drug (ID: DMCQBFT)

Drug Name
Parthenolide
Synonyms
parthenolide; 20554-84-1; (-)-Parthenolide; CHEBI:7939; Parthenolide, Tanacetum parthenium; 4,5-alpha-Epoxy-6-beta-hydroxygermacra-1(10),11(13)-dien-12-oic acid gamma-lactone; partenolide; C15H20O3; 29552-41-8; Prestwick2_000550; Prestwick3_000550; Epitope ID:115014; SCHEMBL8220; BSPBio_001308; BSPBio_000599; MLS002153872; CHEMBL465158; BPBio1_000659; SCHEMBL13367522; BCBcMAP01_000041; Parthenolide, > MolPort-008-268-168; MolPort-003-959-089; HMS1361B10; HMS3402B10; HMS1989B10; HMS1791B10; HMS1569N21; HMS2096N21
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 248.32
Logarithm of the Partition Coefficient (xlogp) 2.3
Rotatable Bond Count (rotbonds) 0
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C15H20O3
IUPAC Name
(1S,2R,4R,7E,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one
Canonical SMILES
C/C/1=C\\CC[C@@]2([C@H](O2)[C@@H]3[C@@H](CC1)C(=C)C(=O)O3)C
InChI
InChI=1S/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5+/t11-,12-,13+,15+/m0/s1
InChIKey
KTEXNACQROZXEV-PVLRGYAZSA-N
Cross-matching ID
PubChem CID
7251185
ChEBI ID
CHEBI:7939
CAS Number
20554-84-1
UNII
2RDB26I5ZB
DrugBank ID
DB13063
TTD ID
D0M4KE
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Inhibitor of nuclear factor kappa-B kinase beta (IKKB) TTJ3E9X IKKB_HUMAN Inhibitor [1]
Nuclear factor NF-kappa-B (NFKB) TTSXVID NFKB1_HUMAN ; NFKB2_HUMAN ; TF65_HUMAN ; RELB_HUMAN ; REL_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Nuclear factor NF-kappa-B (NFKB) DTT NFKB1; NFKB2; RELA; RELB; REL 7.34E-09 0.84 3.94
Inhibitor of nuclear factor kappa-B kinase beta (IKKB) DTT IKBKB 1.28E-03 1.27 2.63
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 205 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 1.4597 2.3248 1.4597 30.5437
JK1 CTRP2 8.8353 15.4596 3.4097 6.6496
JM1 GDSC1; CTRP2 1.0583 1.8361 1.0583 33.2184
HuT 78 CTRP2 -1.0749 3.431 -1.1985 47.5594
697 GDSC1; CTRP2 -0.6224 0.885 -0.6225 44.4155
PL21 CTRP2; CTRP1 0.3066 2.0751 0.3054 38.2896
BCP-1 CTRP2 0.4171 2.3577 0.4078 33.061
NU-DHL-1 CTRP2 0.5242 2.9831 0.5082 36.8281
Hs 611.T CTRP2 0.6139 3.6749 0.5585 36.3554
GA-10 GDSC1; CTRP2 0.6906 1.8269 0.6906 35.6679
Pfeiffer CTRP2 0.8638 1.7689 0.8638 34.5136
ST486 GDSC1; CTRP2 0.873 1.8535 0.873 34.4528
GDM-1 GDSC1; CTRP1 0.9101 2.3775 0.9095 43.8702
SU-DHL-6 GDSC1 0.942 1.5769 0.9372 17.279
P32/ISH GDSC1 1.0028 1.6898 0.9938 16.5459
Daudi GDSC1; CTRP2 1.0236 2.2792 1.0235 33.4496
H9 GDSC1 1.1058 2.3938 0.9744 16.0691
EoL-1 GDSC1; CTRP2 1.116 2.3325 1.1159 32.834
Karpas-231 GDSC1 1.1222 2.3647 1.0007 15.7963
SU-DHL-5 CTRP1 1.1517 1.889 1.1517 70.0932
MOLT-3 CTRP2 1.1779 2.2292 1.1778 32.4215
WIL2 NS GDSC1 1.216 2.1406 1.1593 14.1907
MOLP-8 GDSC1; CTRP2 1.2542 2.2928 1.2542 31.9131
OPM-2 GDSC1; CTRP2 1.2825 2.6215 1.282 31.726
Mino CTRP2 1.2873 1.9994 1.2873 31.6927
A3/Kawakami GDSC1; CTRP2 1.2899 2.7859 1.2886 31.6794
JJN-3 GDSC1; CTRP2 1.3205 2.9197 1.3183 31.4788
Kasumi-2 CTRP2 1.3325 2.3062 1.3325 31.3914
OCI-Ly3 CTRP2 1.3573 2.7837 1.3564 31.2292
QIMR-WIL GDSC1 1.3845 2.7215 1.1675 13.1946
SEM CTRP2 1.4409 2.1274 1.4409 30.6693
NK-92MI GDSC1 1.4545 2.2197 1.4011 11.189
U-937 CTRP2; CTRP1 1.495 3.2625 1.4895 30.3943
WSU-DLCL2 GDSC1; CTRP2; CTRP1 1.5068 2.7412 1.5065 30.2983
SUP-HD1 GDSC1; CTRP2 1.5185 2.8174 1.518 30.1537
NU-DUL-1 GDSC1; CTRP2; CTRP1 1.5371 2.361 1.5371 30.0957
KMS-20 CTRP2 1.5432 2.9136 1.5423 29.9906
MHH-PREB-1 GDSC1 1.5488 3.0488 1.2092 12.0479
Sc-1 GDSC1 1.5753 2.343 1.5012 9.8204
CA46 GDSC1; CTRP2 1.5858 3.0037 1.5845 29.708
SCC-3 GDSC1 1.6084 3.1113 1.2436 11.4996
OCI-Ly19 GDSC1; CTRP2 1.6307 3.3627 1.6249 29.424
MLMA GDSC1 1.6496 2.3249 1.5873 8.813
Loucy GDSC1 1.6547 2.3146 1.5957 8.727
Farage GDSC1 1.6637 2.4681 1.5589 8.9296
LP-1 GDSC1; CTRP2; CTRP1 1.6725 2.6733 1.6725 40.9791
SU-DHL-16 GDSC1 1.6883 2.1913 1.6612 8.095
SUP-B15 GDSC1; CTRP2 1.7204 3.0403 1.7195 28.8101
SUP-M2 GDSC1; CTRP2 1.7246 2.7908 1.7245 28.7793
MOTN-1 CTRP2 1.7306 2.9509 1.7301 28.7408
EB1 CTRP2 1.7393 3.3239 1.7356 28.6933
HC-1 GDSC1 1.8084 3.1388 1.4338 9.1172
Ci-1 CTRP2 1.8222 2.3333 1.8222 28.1287
VAL GDSC1 1.8291 3.7845 1.1481 11.209
DND-41 GDSC1; CTRP2 1.8762 3.0525 1.8757 27.7706
Granta-519 GDSC1; CTRP2 1.896 4.8204 1.783 28.0193
M-07e CTRP2 1.9173 2.7874 1.9173 27.4951
CTB-1 GDSC1 1.9186 3.6429 1.3012 9.6398
OCI-AML-2 GDSC1 1.9445 2.4474 1.8701 5.2204
A4/Fukuda GDSC1; CTRP2 1.9598 3.0045 1.9584 22.0218
THP-1 GDSC1; CTRP1 1.976 2.9103 1.976 34.7865
NOMO-1 GDSC1; CTRP1 2.0009 2.655 2.0009 34.5748
EJM GDSC1; CTRP2; CTRP1 2.008 4.2012 1.9741 27.0753
SET-2 CTRP2 2.0162 3.0386 2.016 26.837
KO52 CTRP2 2.0212 2.9664 2.0205 21.581
HAL-01 GDSC1 2.0277 4.0603 1.1969 9.9964
Namalwa GDSC1; CTRP2 2.0468 3.3011 2.0458 26.6357
MY-M12 GDSC1 2.0516 4.0182 1.2391 9.5699
NB4 GDSC1 2.1377 3.0369 1.8013 4.8253
OCI-AML-3 GDSC1; CTRP2; CTRP1 2.1458 2.9281 2.1458 26.0447
SU-DHL-4 GDSC1; CTRP2; CTRP1 2.171 3.1965 2.1708 25.8775
AML-193 CTRP2 2.1791 3.0443 2.1791 25.751
Ramos.2G6.4C10 GDSC1 2.1855 3.6108 1.5605 6.5183
HH [Human lymphoma] GDSC1; CTRP2 2.1928 3.1212 2.1927 25.6603
Karpas-422 GDSC1; CTRP2 2.2036 3.0225 2.2036 25.5877
ATN-1 GDSC1 2.2097 3.2237 1.7744 4.7422
Mono-Mac-6 GDSC1 2.2157 4.625 1.0807 10.1701
CESS GDSC1 2.2172 3.6403 1.5736 6.2921
U266B1 GDSC1; CTRP2 2.2285 3.1133 2.2285 25.422
KMS-11 CTRP2; CTRP1 2.2297 3.3083 2.2297 37.8882
MV4-11 GDSC1 2.305 3.7947 1.5714 5.9809
JeKo-1 CTRP2 2.3288 3.072 2.3288 24.7541
RPMI-8866 GDSC1 2.3337 3.6995 1.6429 5.3128
CCRF-CEM GDSC1 2.372 3.6442 1.702 4.7108
Reh GDSC1 2.3746 3.6773 1.6876 4.8155
LAMA-84 GDSC1 2.378 4.0717 1.4933 6.3347
RPMI-8226 GDSC1; CTRP2; CTRP1 2.3793 3.6315 2.3775 24.4966
OCI-Ly10 CTRP2; CTRP1 2.4042 4.9594 2.3966 36.9405
HL-60 GDSC1; CTRP2 2.4341 3.9353 2.4272 24.0752
SIG-M5 GDSC1; CTRP2 2.4383 3.0123 2.4383 18.6014
U-698-M GDSC1 2.4476 5.5467 0.813 11.3973
Kasumi-1 GDSC1; CTRP2 2.4568 3.249 2.4568 23.9012
HD-MY-Z CTRP2 2.4712 3.3549 2.4711 23.8056
RPMI-6666 GDSC1; CTRP2 2.4883 3.2228 2.4883 23.6911
TK [Human B-cell lymphoma] GDSC1 2.5272 3.8294 1.7316 3.9629
DB GDSC1; CTRP2 2.5709 3.5112 2.5706 23.142
KE-37 GDSC1 2.6044 3.9431 1.733 3.7165
RL GDSC1; CTRP2 2.6399 3.1593 2.6399 22.6812
NKM-1 GDSC1 2.6708 4.4133 1.5508 4.9284
BC-1 GDSC1 2.6752 4.1401 1.6878 3.8576
Jiyoye GDSC1 2.6754 5.5203 1.0069 9.1338
SKM-1 GDSC1; CTRP2; CTRP1 2.7343 3.338 2.7343 22.1278
F-36P CTRP2 2.7596 4.5381 2.7321 21.9765
L-428 GDSC1; CTRP2 2.797 3.9077 2.7953 21.6404
KG-1 GDSC1 2.8592 4.4154 1.682 3.4009
OCI-M1 GDSC1; CTRP2 2.8729 3.9789 2.8596 15.5469
MOLT-4 GDSC1 2.9226 4.355 1.7517 2.7302
MOLT-16 GDSC1 2.931 4.7824 1.5548 4.1673
MOLM-16 CTRP2; CTRP1 2.9508 4.3797 2.9399 20.723
VL51 GDSC1 2.9895 5.7706 1.1173 7.3216
OCI-AML-5 GDSC1; CTRP2 3.0273 4.4211 3.0165 20.1362
BC-3 GDSC1 3.0276 4.6979 1.658 3.1644
HEL 92.1.7 CTRP2 3.0364 4.3123 3.001 14.4607
PF-382 GDSC1 3.0551 6.6878 0.7158 10.1419
PL-21 GDSC1 3.0719 5.4265 1.3414 5.3976
Karpas-45 GDSC1 3.1342 6.9534 0.6433 10.4353
ME1 GDSC1 3.156 4.9588 1.6167 3.1676
MN-60 GDSC1 3.2033 6.0753 1.1193 6.7095
ALL-PO GDSC1 3.204 9.5112 -0.5667 18.19
KMOE-2 GDSC1 3.2623 6.4829 0.9634 7.7089
IM-9 GDSC1 3.3127 10.6746 -1.0602 20.5259
BALL-1 GDSC1 3.3159 9.5582 -0.5049 17.4767
ML-2 GDSC1 3.3329 13.9301 -2.6627 27.1452
Raji GDSC1 3.3659 6.1777 1.1792 5.8449
Toledo CTRP2 3.3678 6.1798 3.0853 18.824
AMO1 GDSC1; CTRP2; CTRP1 3.4453 4.2444 3.4453 31.144
DoHH2 GDSC1 3.7183 5.1794 1.8215 0.9603
BL-70 CTRP2; CTRP1 3.7281 4.9189 3.6422 9.8071
RC-K8 GDSC1 3.7862 6.0315 1.4985 2.732
L-1236 GDSC1 3.8084 5.8059 1.6073 2.0233
MHH-CALL-4 CTRP2 3.8117 9.5048 2.2249 20.8332
JVM-2 GDSC1 3.86 7.5655 0.8443 7.0452
KY821 GDSC1 3.8902 9.079 0.1442 11.7483
DEL GDSC1; CTRP2 3.9171 4.6651 3.9158 14.1769
TF-1 CTRP2 3.9367 5.2254 3.9053 14.1478
YT GDSC1 4.0185 5.6259 1.7797 0.8579
Hs 445 GDSC1 4.0318 5.6984 1.7574 0.9462
GR-ST GDSC1 4.0601 7.449 1.0212 5.3765
LC4-1 GDSC1 4.0861 5.9819 1.6698 1.3124
ARH-77 GDSC1 4.1085 12.1886 -1.2133 18.9353
CMK CTRP2 4.2823 5.8662 4.1669 12.1392
K-562 GDSC1; CTRP2 4.2868 5.6758 3.9884 6.5969
TUR GDSC1 4.3487 6.1449 1.7217 0.8223
MOLM-13 GDSC1; CTRP2 4.4406 5.3756 4.4214 10.7492
SK-MM-2 GDSC1 4.5534 6.1112 1.8154 0.3728
ROS-50 GDSC1 4.5899 6.7869 1.5784 1.2304
EB2 GDSC1 4.5911 6.438 1.7115 0.6838
MEG-01 GDSC1 4.6217 6.9408 1.5322 1.4137
Karpas-299 GDSC1 4.6225 6.1628 1.823 0.3231
TALL-1 [Human adult T-ALL] CTRP2 4.6582 7.0331 4.1813 10.9973
CTV-1 GDSC1 4.7139 15.5668 -2.4283 22.5328
HDLM-2 GDSC1 4.835 7.1617 1.5397 1.1787
P30/OHK GDSC1 4.9245 13.5276 -1.2883 17.1542
KMS-12-BM GDSC1; CTRP2 5.1115 6.4217 4.9031 6.9694
WSU-NHL GDSC1 5.1187 14.53 -1.6378 18.2956
DG-75 GDSC1 5.1217 13.5595 -1.1697 16.0957
BE-13 GDSC1 5.3874 7.2334 1.7287 0.2698
BL-41 GDSC1; CTRP2 5.5391 6.8281 5.1797 4.7441
MM1.S CTRP2 5.875 7.3272 3.6076 0.3279
MC116 GDSC1; CTRP2; CTRP1 7.2692 8.269 5.7138 0.1988
KMM-1 CTRP2 7.3788 9.8815 5.0908 2.0483
SU-DHL-10 CTRP2 7.4884 8.4569 5.7306 0.1089
KE-97 CTRP2; CTRP1 7.5128 9.7019 5.2458 1.3688
ALL-SIL GDSC1; CTRP2 7.5642 10.0118 5.1384 1.6887
RPMI-8402 GDSC1; CTRP2 7.6816 9.4467 5.4369 0.6554
SU-DHL-1 GDSC1; CTRP2 7.7406 8.8042 5.7016 0.0956
P31/FUJ GDSC1; CTRP2 7.7596 8.8136 5.7052 0.0882
KYO-1 CTRP2 7.7862 9.3354 5.5265 0.3813
KHM-1B CTRP2 7.8068 9.5811 5.4404 0.5748
P12-Ichikawa CTRP2 7.8115 9.252 5.5682 0.2854
KMS-34 CTRP2 7.8458 9.4151 5.5212 0.3674
Jurkat CTRP2 7.87 9.2333 5.5981 0.2125
P3HR-1 CTRP2; CTRP1 7.9011 9.8456 5.3783 0.6824
NALM-6 GDSC1; CTRP2 7.9014 9.5426 5.4962 0.3979
EM-2 GDSC1; CTRP2 7.9176 9.6594 5.4584 0.4752
L-540 GDSC1; CTRP2 7.9516 9.4211 5.5618 0.2502
KMS-21-BM CTRP2 7.9548 9.9577 5.3582 0.7042
JURL-MK1 GDSC1; CTRP2 7.9802 9.5722 5.5175 0.3227
Karpas-620 CTRP2 8.0053 9.416 5.5844 0.1971
SU-DHL-8 GDSC1; CTRP2 8.0126 9.6614 5.4975 0.3504
HEL GDSC1; CTRP2 8.075 9.2098 5.6814 0.0668
ME1 CTRP2 8.1071 9.4327 5.6164 0.1295
HPB-ALL CTRP2 8.1352 9.3572 5.6525 0.0853
KM-H2 GDSC1; CTRP2 8.1675 9.583 5.586 0.1561
HT GDSC1; CTRP2; CTRP1 8.1961 9.4887 5.6291 0.0998
SUP-T11 CTRP2 8.211 9.7103 5.5573 0.1861
Peer CTRP2 8.268 9.5532 5.6325 0.0861
L-363 GDSC1; CTRP2 8.2789 9.5807 5.627 0.0898
SR GDSC1; CTRP2 8.3102 9.8644 5.5398 0.1877
MOLP-2 CTRP2 8.3146 9.9082 5.526 0.2067
SUP-T1 GDSC1; CTRP2 8.3389 9.7386 5.5942 0.1142
MOLM-6 CTRP2 8.3456 10.0393 5.4909 0.2531
EHEB CTRP2 8.3744 10.0699 5.4909 0.2451
RCH-ACV CTRP2 8.4579 10.1191 5.505 0.2027
Ku812 GDSC1; CTRP2; CTRP1 8.46 10.099 5.5129 0.1912
KCL-22 GDSC1; CTRP2 8.5071 10.184 5.5004 0.1978
BV-173 GDSC1; CTRP2 8.5207 10.0141 5.5645 0.1169
JVM-3 GDSC1; CTRP2 8.5961 10.4299 5.4465 0.2555
RS4;11 GDSC1; CTRP2 8.7461 10.3153 5.5413 0.1071
KMS-18 CTRP2 8.7813 10.3784 5.5322 0.1109
REC-1 CTRP2 8.7877 10.7093 5.4194 0.2477
Ri-1 CTRP2 8.8444 11.9365 4.9759 1.2016
KMS-28BM CTRP2 8.8817 10.962 5.3648 0.3075
MHH-CALL-3 CTRP2 9.1322 11.2987 5.3397 0.2806
Mono-Mac-1 CTRP2 9.364 11.816 5.2427 0.3703
⏷ Show the Full List of 205 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 4.4533 6.3977 4.2001 11.5035
TE8 CTRP2 8.4193 9.768 5.6126 0.0845
TE-5 GDSC1; CTRP2 1.4305 2.9407 1.4288 30.7439
TE-9 GDSC1 2.3857 3.3466 1.8617 3.4051
TE-10 GDSC1 3.029 4.7077 1.6542 3.1883
KYSE-150 CTRP2 3.3112 4.5389 3.3028 18.237
KYSE-30 CTRP2 3.961 5.246 3.9287 13.9889
TE-14 CTRP2 4.018 6.09 3.8203 14.1932
OE33 CTRP2 4.1195 5.7419 3.7857 7.9266
EC-GI-10 GDSC1; CTRP2 4.4559 5.7041 4.3905 10.807
OE19 CTRP2 4.6056 4.982 4.581 3.223
OE21 CTRP2 4.6315 6.3092 4.4227 10.1558
KYSE-520 CTRP2 4.8507 6.5834 4.1081 4.6351
TE-15 GDSC1 5.2685 7.3971 1.6276 0.5649
TE-8 GDSC1 5.4049 7.5266 1.633 0.4857
KYSE-510 CTRP2 5.469 6.15 5.3847 4.1333
TE-11 CTRP2 5.697 7.6814 4.2221 2.5512
KYSE-410 CTRP2; CTRP1 5.9132 6.9287 5.4886 2.6024
TE-6 GDSC1; CTRP2 6.6338 8.1424 5.4365 1.6161
KYSE-450 CTRP2; CTRP1 6.7029 8.2881 4.5228 0.5016
KYSE-70 CTRP2 6.9444 9.0136 5.226 2.0413
KYSE-180 CTRP2 8.1586 9.5213 5.6043 0.1344
TE-1 GDSC1; CTRP2 8.306 10.2053 5.4142 0.4061
TE-4 CTRP2 8.3449 9.9551 5.5207 0.207
KYSE-140 CTRP2; CTRP1 8.3946 10.6598 5.2784 0.6691
COLO 680N CTRP2 8.5237 9.93 5.5942 0.0877
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 4.3944 7.2475 3.3633 9.0307
Panc 08.13 CTRP2 2.644 4.0882 2.6366 22.6786
HuP-T3 CTRP2 2.6945 5.4474 2.3595 18.0473
MIA PaCa-2 CTRP2 2.8666 4.7868 2.7328 16.0403
PaTu 8988s CTRP2 3.2377 4.6653 3.2207 18.7557
Capan-2 CTRP2; CTRP1 3.4934 4.6936 3.4832 17.0293
AsPC-1 CTRP2 3.6254 5.5373 3.5236 16.4645
Capan-1 CTRP2 3.9314 5.6442 3.626 9.1402
PSN1 GDSC1; CTRP2 3.9775 5.4777 3.9144 13.985
PK-45H CTRP2 4.0972 9.1855 2.1398 15.1221
Panc 10.05 CTRP2; CTRP1 4.1232 5.0293 4.1154 12.8253
SW1990 CTRP2 4.4878 5.8206 4.4011 10.6692
Panc 02.03 CTRP2 4.503 5.2856 4.4937 10.3002
Hs 766T CTRP2 4.5986 6.331 4.38 10.4106
Panc 04.03 CTRP2 4.7168 5.9507 4.2958 4.1158
PaTu 8988t CTRP2 4.7469 5.1966 4.7461 8.6468
MZ-PC-1 GDSC1 4.8962 7.1635 1.565 1.0222
DAN-G CTRP2 4.9469 5.7374 4.9144 7.4226
KP-2 CTRP2 5.2162 5.9068 5.1741 5.6623
KP-4 CTRP2 5.4856 7.2675 4.9218 5.9207
Panc 03.27 CTRP2; CTRP1 5.5626 6.0307 5.5223 3.3504
SU.86.86 CTRP2 6.0697 6.9356 5.6197 1.737
HPAC CTRP2; CTRP1 7.2128 9.1287 4.4183 0.5048
PK-59 CTRP2 7.2238 8.9984 3.5194 0.1261
SNU-410 CTRP2 7.4748 11.4043 4.4423 4.421
TCC-Pan2 CTRP2 7.5362 9.2446 5.4504 0.7096
CFPAC-1 CTRP2; CTRP1 7.569 15.288 2.6234 11.4805
SNU-213 CTRP2 7.5926 8.7606 5.6617 0.1874
L3.3 CTRP2 7.6607 20.7605 -0.0139 20.1409
Panc 05.04 CTRP2 7.8723 9.308 5.5719 0.2576
PaTu 8902 CTRP2; CTRP1 8.1796 12.4212 4.4108 3.674
SUIT-2 CTRP2; CTRP1 8.1942 9.6557 5.5703 0.1716
KP-3 CTRP2; CTRP1 8.5502 11.0813 5.1823 0.8255
HuP-T4 CTRP2; CTRP1 8.571 10.0806 5.5595 0.1143
QGP-1 CTRP2; CTRP1 8.572 10.2574 5.4986 0.186
HPAF-II CTRP2 8.8552 10.5648 5.4947 0.138
BxPC-3 CTRP2 9.2142 11.0645 5.451 0.1286
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 60 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 6.5682 21.5423 -1.2725 25.3352
COLO 792 CTRP2 1.9561 3.9705 1.9351 27.3071
A-388 GDSC1 1.9889 3.5748 1.4002 8.5726
DJM-1 GDSC1 1.9981 3.024 1.6745 6.4138
LB2518-MEL GDSC1 2.1173 3.1733 1.7156 5.5786
MZ-MEL-2 GDSC1 2.2214 3.4738 1.6602 5.5948
Hs 688(A).T CTRP2 2.2675 3.9513 2.2565 25.1992
SH-4 GDSC1 2.4479 4.228 1.4717 6.2621
MZ-MEL-7 GDSC1 2.4905 4.8285 1.2062 8.2017
MMAc-SF GDSC1 2.5104 3.5848 1.8398 3.1719
GAK GDSC1 2.5485 4.1708 1.5788 5.0899
SK-MEL-1 GDSC1; CTRP1 2.8019 3.4746 2.8019 27.7498
A-375 CTRP2; CTRP1 2.8465 4.9607 2.7805 21.6042
MeWo CTRP2 2.8495 4.6623 2.8158 21.3984
CP66-MEL GDSC1 2.8897 4.7528 1.5409 4.3813
WT2-iPS CTRP2 3.2902 5.034 3.2422 18.5111
WM266-4 CTRP2 3.3118 4.7476 3.2921 18.271
COLO 800 GDSC1; CTRP2 3.4633 5.1931 3.4061 17.3893
UACC-257 GDSC1; CTRP2 3.5047 5.7455 3.3482 17.461
Hs 940.T CTRP2 3.5687 5.7529 3.4162 17.0208
IGR-1 CTRP2 3.5809 10.3788 1.5918 23.7308
LB373-MEL-D GDSC1 3.6257 5.4825 1.6503 2.0465
WM88 CTRP2 3.6855 5.482 3.599 16.011
Hs 294T CTRP2 3.8102 5.2247 3.7713 15.016
K029AX CTRP2 4.0141 8.2722 2.508 13.731
SK-MEL-5 CTRP2; CTRP1 4.018 4.906 4.0129 13.6007
SK-MEL-2 GDSC1; CTRP2 4.0247 6.2624 3.7771 14.3301
WM115 CTRP2 4.3547 5.8672 4.2455 11.6352
HT-144 GDSC1; CTRP2 4.3808 5.6419 4.3208 11.2883
HMCB CTRP2 4.4349 4.8886 4.4347 10.7233
IST-MEL1 GDSC1 4.5261 6.2516 1.7542 0.5757
CJM [Human melanoma] CTRP2 4.5692 4.9745 4.5691 9.8285
RVH-421 CTRP2 4.5882 4.9893 4.588 9.702
SK-MEL-24 CTRP2 4.5935 6.132 4.4362 10.2196
UACC-62 CTRP2 4.6132 5.8207 4.5374 9.7957
Hs 839.T CTRP2 4.6214 5.1848 4.6195 9.4865
WM983B CTRP2 4.6721 6.0091 4.5563 9.5467
A101D GDSC1; CTRP2 4.6737 5.0518 4.6736 9.1322
SK-MEL-28 CTRP2; CTRP1 4.6895 15.4321 0.1873 25.4968
COLO 829 GDSC1; CTRP2 4.7094 6.4899 4.4454 9.8447
SK-MEL-3 CTRP2 4.7229 5.5008 4.7063 8.8601
IGR-39 CTRP2 4.7493 5.2382 4.7479 8.6328
A2058 CTRP2 5.0548 5.8627 5.008 6.7537
Hs 895.T CTRP2 5.2137 5.9768 5.1553 5.737
IGR-37 CTRP2 5.3289 6.6687 5.0352 5.8617
LOX-IMVI GDSC1; CTRP2 5.4067 8.3157 4.3416 8.4911
WM1799 CTRP2 6.1446 7.4368 3.671 0.1344
G-361 CTRP2; CTRP1 6.2256 8.9392 3.9834 2.8923
WM793 CTRP2 6.4833 7.8147 3.6617 0.0882
Hs 852.T CTRP2; CTRP1 6.9434 9.005 4.3476 0.8424
RPMI-7951 CTRP2 7.3219 9.3256 5.3063 1.338
Hs 936.T CTRP2; CTRP1 7.391 8.5347 4.6951 0.0418
SK-MEL-30 CTRP2 7.4354 11.2307 4.4987 4.251
MDA-MB-435S CTRP2 7.5424 9.028 5.5398 0.4665
IPC-298 CTRP2 7.6469 9.0444 5.5784 0.328
Mel Ho CTRP2 7.9266 9.3984 5.5602 0.2609
SK-MEL-31 CTRP2 8.2226 9.7204 5.5581 0.1823
Mel JuSo CTRP2 8.2357 9.7153 5.5648 0.17
Hs 944.T CTRP2; CTRP1 8.4701 9.9575 5.5658 0.1236
COLO 741 CTRP2; CTRP1 8.55 11.1929 5.138 0.9406
⏷ Show the Full List of 60 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-12 GDSC1 3.4458 7.6507 0.5261 10.3711
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 2.0669 3.0873 2.0667 26.4994
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-13 GDSC1 1.3689 2.2271 1.3061 12.321
SK-N-DZ GDSC1; CTRP2 1.3839 2.334 1.3839 31.049
SK-N-BE(2) CTRP2 1.4944 2.9937 1.4927 30.3185
SJNB-10 GDSC1 1.5318 2.4476 1.4223 10.6061
GI-ME-N GDSC1 1.6458 3.8483 0.9416 13.6017
SJNB-14 GDSC1 1.7423 2.2766 1.7012 7.5133
SJNB-7 GDSC1 1.8036 2.3321 1.7534 6.8095
IMR-32 CTRP2 1.8155 2.4539 1.8155 23.0466
SK-N-SH CTRP2 1.8798 2.7908 1.8797 27.7455
LA-N-6 GDSC1 2.1689 3.0697 1.814 4.5971
SK-N-FI GDSC1; CTRP2 2.2298 3.0646 2.2293 20.0912
SJNB-17 GDSC1 2.2819 4.6697 1.1145 9.6596
NH-12 GDSC1 2.6873 4.4458 1.547 4.9086
SK-N-AS CTRP2 2.6935 4.7701 2.5482 17.3183
CHP-212 CTRP2 2.7364 5.5908 2.3577 17.922
KP-N-YN GDSC1; CTRP2 2.8041 5.0296 2.7247 21.857
NH-6 CTRP2 3.4573 5.1818 3.4012 17.4257
SiMa GDSC1 3.5844 5.9649 1.414 3.6731
TGW GDSC1 3.6426 5.3322 1.7228 1.5872
GOTO GDSC1 3.7628 7.7502 0.6942 8.336
SK-N-BE(2)-M17 GDSC1 3.7842 5.6135 1.6759 1.6575
SJNB-5 GDSC1 3.827 5.8307 1.6063 2.0013
KP-N-YS GDSC1 3.8395 5.7887 1.6303 1.8419
NB(TU)1 GDSC1 3.9231 5.6199 1.7396 1.1433
IMR-5 GDSC1 3.9303 5.407 1.8261 0.7344
MHH-NB-11 GDSC1 4.2499 5.9979 1.736 0.8443
SJNB-6 GDSC1 4.2991 6.3017 1.6395 1.2324
SJNB-12 GDSC1 4.3661 6.902 1.4277 2.2643
NB69 GDSC1 4.9885 7.0016 1.6622 0.6072
CHP-126 GDSC1; CTRP2 7.2835 9.4702 5.2207 1.6777
Kelly GDSC1; CTRP2 7.6306 8.8729 5.6356 0.2213
NB1 GDSC1; CTRP2 8.4377 9.6759 5.6498 0.0533
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-869 CTRP2 4.3649 5.6336 4.3051 11.3935
HuCC-T1 CTRP2 7.0706 9.2791 5.1813 2.06
SNU-245 CTRP2 7.1035 9.8893 4.9167 3.0432
SNU-1079 CTRP2 8.1668 10.1705 5.3689 0.5655
SNU-1196 CTRP2 8.3033 10.168 5.427 0.3816
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-673 CTRP2 1.9451 3.0948 1.9447 27.3113
SK-PN-DW GDSC1 1.9641 3.1974 1.5592 7.4498
ES1 GDSC1 2.2407 4.8251 1.002 10.6898
G-292 clone A141B1 CTRP2 2.277 3.3332 2.2767 25.0999
SK-N-MC CTRP2 2.4042 3.9347 2.3968 24.2763
SK-ES-1 GDSC1; CTRP2 2.4337 3.3326 2.4336 24.0551
ES8 GDSC1 2.5526 4.0203 1.6565 4.4695
EW-12 GDSC1 2.5652 4.2424 1.5561 5.214
MG-63 CTRP2 2.723 3.9695 2.7198 22.1383
Hs 822.T CTRP2 2.8274 3.9442 2.8256 21.4378
EW-13 GDSC1 2.9372 5.4868 1.2183 6.7038
SaOS-2 CTRP2 2.947 4.4488 2.9325 20.6839
Hs 888.T CTRP2 3.1998 5.5287 3.064 19.4178
EW-18 GDSC1 3.2842 6.4859 0.9771 7.5474
EW-3 GDSC1 3.8037 6.4413 1.3268 3.8274
EW-1 GDSC1 4.076 6.0306 1.6454 1.4492
TC-71 GDSC1 4.0866 5.7843 1.748 0.937
EW-22 GDSC1 4.2681 6.2913 1.6297 1.3124
EW-24 GDSC1 4.289 5.3549 1.9815 0.1042
ES6 GDSC1 4.3888 6.5837 1.5684 1.4845
TC71 CTRP2 4.4741 4.9668 4.4737 10.463
NOS-1 [Human HNSCC] GDSC1 4.6054 6.9288 1.5296 1.4427
HOS CTRP2 4.7074 5.9815 4.6019 9.2746
EW-16 GDSC1 5.0004 6.8831 1.7094 0.4601
ES4 GDSC1 5.2958 7.2452 1.6916 0.3816
H-EMC-SS GDSC1 5.4478 7.794 1.5536 0.6957
ES7 GDSC1 5.4749 7.5628 1.6462 0.4226
ES5 GDSC1 5.5421 8.1524 1.4596 0.9549
EW-11 GDSC1 6.0426 8.3877 1.5659 0.4022
SW1353 CTRP2 7.9053 9.2923 5.5905 0.215
MHH-ES-1 CTRP2 8.0869 9.8148 5.4706 0.3763
CAL-78 CTRP2 8.3631 9.7526 5.598 0.1063
U2OS CTRP2 8.5457 10.3661 5.4501 0.2632
SJSA-1 GDSC1; CTRP2 8.8433 10.453 5.5286 0.1058
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 77 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-BR-3 CTRP2 1.3433 3.4548 1.329 31.367
MDA-MB-157 CTRP2 1.7604 2.8907 1.7602 28.5413
Evsa-T GDSC1 1.7945 2.3954 1.7247 7.0563
MDA-MB-468 CTRP2 1.9309 4.3458 1.88 27.5759
OCUB-M GDSC1 2.0635 3.5696 1.4715 7.706
Hs 578T CTRP2 2.1326 4.5248 2.0743 26.2576
MRK-nu-1 GDSC1 2.2856 5.2525 0.8263 11.8815
HCC38 CTRP2 2.3429 3.4043 2.3425 24.6611
MDA-MB-361 CTRP2 2.3902 3.7139 2.3874 24.3539
HCC1500 GDSC1; CTRP2 2.4459 3.5991 2.4448 23.9777
HCC2218 GDSC1; CTRP2 2.4527 3.2288 2.4526 23.9287
DU4475 GDSC1; CTRP2 2.4845 3.1391 2.4845 23.7167
T-47D CTRP2 2.4922 3.851 2.4882 23.6785
MDA-MB-453 CTRP2 2.6401 4.4364 2.6151 22.7637
AU565 CTRP2 2.6595 4.8874 2.59 22.786
Hs 578Bst CTRP2 2.6822 3.133 2.6822 22.3996
BT-20 CTRP2 2.7168 4.5061 2.6283 16.9378
BT-474 GDSC1; CTRP2 2.7436 3.6383 2.7434 21.991
ZR-75-30 CTRP2 2.8698 5.1888 2.7704 21.4886
HCC1187 GDSC1 2.9273 4.8956 1.4979 4.605
HCC1599 GDSC1 2.962 5.3869 1.2846 6.1279
MDA-MB-415 CTRP2 3.0833 4.138 3.0813 19.734
HCC1428 CTRP2 3.0996 5.4549 2.9703 20.062
HCC2157 GDSC1 3.2112 4.6713 1.7795 1.9346
HCC202 CTRP2 3.2666 8.8279 1.5238 19.8158
EFM-192A CTRP2 3.3552 5.1936 3.2905 18.1353
UACC-812 GDSC1 3.395 5.0941 1.695 2.1542
CAL-85-1 CTRP2 3.4723 5.3492 3.392 17.4094
BT-549 CTRP2 3.4872 5.4359 3.2239 12.1239
HCC1419 CTRP2 3.5639 5.8841 3.3794 17.1666
CAL-148 GDSC1 3.9796 5.5275 1.8009 0.7997
MCF-7 CTRP2; CTRP1 4.3839 5.7732 4.3002 11.436
MFM-223 GDSC1 4.5524 6.067 1.8307 0.3324
COLO 824 GDSC1 5.5052 7.3139 1.7428 0.213
HDQ-P1 CTRP2 6.7138 8.872 5.1421 2.6789
ZR-75-1 CTRP2 6.7866 9.7065 4.789 4.0052
KPL-1 CTRP2 7.0328 7.8135 5.7873 0.1423
HCC1143 CTRP2 7.572 9.6629 3.4157 0.1849
JIMT-1 CTRP2 7.9421 9.6115 5.4871 0.4002
CAL-120 CTRP2 8.2805 9.5372 5.6422 0.0757
HCC1954 CTRP2 8.3258 10.1056 5.4591 0.3135
CAMA-1 CTRP2 8.3634 9.7226 5.6084 0.0959
HMC-1-8 CTRP2 8.3734 9.4583 5.6999 0.0293
HCC1806 CTRP2 8.4544 11.7451 4.8635 1.8195
MDA-MB-231 CTRP2 8.6891 10.6156 5.4154 0.2793
CAL-51 CTRP2 15.0611 36.3099 -2.3963 16.2248
BT 239 CTRP2 1.9658 2.8573 1.9657 27.1726
BT 112 CTRP2 2.256 3.0964 2.2559 25.2391
BT164 CTRP2 2.3082 3.6153 2.306 24.8985
BT 231 CTRP2 2.3345 3.2272 2.3344 24.7162
BT 145 CTRP2 2.433 3.8129 2.429 24.0729
BT 159 CTRP2 2.4485 2.8995 2.4485 23.9564
BT 286 CTRP2 2.5671 2.9903 2.5671 23.1665
BT 271 CTRP2 2.598 3.1683 2.598 22.9605
BT 131 CTRP2 2.6148 3.0217 2.6148 22.8482
BT 422 CTRP2 2.6434 3.2418 2.6434 22.6582
BT 504 CTRP2 2.6586 3.0127 2.6586 22.5564
BT 139 CTRP2 2.7506 3.1743 2.7506 21.9434
BT 333 CTRP2 2.7592 3.4205 2.7592 21.8866
BT 330 CTRP2 2.7597 3.4885 2.7596 21.8833
BT 245 CTRP2 2.78 3.5864 2.7799 21.7484
BT 340 CTRP2 2.8213 3.2948 2.8213 21.4725
BT 444 CTRP2 2.823 3.8654 2.822 21.4648
BT 359 CTRP2 2.8454 4.2569 2.8366 21.3416
BT 172 CTRP2 3.0264 4.2796 3.0207 20.1253
BT147 CTRP2 3.0741 4.1579 3.0717 19.7967
BT 416 CTRP2 3.0885 4.1376 3.0866 19.699
BT 248 CTRP2 3.7125 4.3555 3.7123 15.5361
BT 482 CTRP2 3.7304 5.5311 3.6384 15.7311
BT 498 CTRP2 3.8109 5.3366 3.7574 15.0614
BT 328 CTRP2 3.8129 5.1548 3.7821 14.9703
BT 232 CTRP2 4.3235 5.4455 4.2896 11.5796
BT 440 CTRP2 4.3328 5.4153 4.3032 11.5031
BT 179 CTRP2 4.3421 4.8841 4.3416 11.3425
BT 216 CTRP2 4.4964 6.7785 4.1101 11.7186
BT 224 CTRP2 4.9316 6.6422 4.1496 4.2689
BT 320 CTRP2 5.7345 6.1658 5.6667 2.3096
⏷ Show the Full List of 77 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Onda 10 GDSC1 0.3758 3.6494 -0.2691 28.4728
SF539 GDSC1; CTRP2 1.3675 3.0426 1.3642 31.1695
D-247MG GDSC1 2.1304 3.7632 1.4361 7.7122
KS-1 [Human Krukenberg tumour] GDSC1 2.1708 5.2925 0.7089 13.2085
GI-1 GDSC1 2.3239 3.6032 1.6829 5.0322
SW1783 CTRP2 2.404 5.7748 2.1418 25.1572
Onda 11 GDSC1 2.4063 4.242 1.4313 6.7236
D-542MG GDSC1 2.4943 3.7056 1.768 3.7826
D283 Med GDSC1; CTRP2 2.6343 4.0826 2.6011 17.3225
D-336MG GDSC1 2.7192 4.4607 1.5629 4.6918
KNS-81-FD GDSC1 2.7999 4.808 1.4512 5.3165
D-392MG GDSC1 2.886 5.0013 1.4183 5.3234
YH-13 CTRP2 3.3348 5.5965 3.1965 18.5275
AM-38 GDSC1 3.4711 5.4596 1.5757 2.8
D-502MG GDSC1 3.4899 6.6203 1.0508 6.4721
GMS-10 CTRP2 3.521 5.4327 3.4302 17.1217
GOS-3 CTRP2 3.6408 4.9723 3.6182 16.089
YKG-1 CTRP2 3.7783 5.7135 3.6532 15.5286
A-172 CTRP2 3.9721 15.5101 -0.5098 28.9711
D-263MG GDSC1 4.0865 5.4375 1.8785 0.424
TM-31 CTRP2 4.1964 5.1847 4.1818 12.3608
U-118MG CTRP2 4.2122 5.8436 4.0959 12.6087
SF268 GDSC1; CTRP2 4.2454 6.1151 4.0613 12.6314
M059K CTRP2 4.3111 5.5259 4.265 11.7042
DK-MG CTRP2 4.3751 5.6188 4.3187 11.3135
KNS-42 GDSC1; CTRP2 4.3835 5.4505 4.1825 5.5085
Hs 683 CTRP2 4.4039 4.9737 4.4029 10.9326
KINGS-1 GDSC1 4.4487 6.518 1.6212 1.1701
8-MG-BA GDSC1; CTRP2 4.4521 5.0652 4.4502 10.6145
Becker GDSC1; CTRP2 4.4673 5.5845 4.4235 10.6561
LN-229 CTRP1 4.5086 5.744 4.4414 22.641
Daoy CTRP2 4.7925 6.9771 4.3454 9.9958
U-251MG CTRP2 4.8645 6.166 4.7216 8.3651
42-MG-BA CTRP2 4.9052 6.0843 4.79 7.9937
CCF-STTG1 CTRP2 5.2017 5.913 5.1569 5.7685
SNB-75 GDSC1; CTRP2 5.3635 6.192 5.2563 4.9185
KG-1-C CTRP2 5.417 5.9111 5.391 4.2689
GB-1 GDSC1; CTRP2 5.9869 8.6613 4.6877 5.8146
CAS-1 GDSC1; CTRP2 6.2077 8.4203 4.9896 4.1283
SNU-738 CTRP2 6.5142 9.274 4.8024 4.3809
KNS-60 CTRP2 6.5495 7.6779 5.6004 1.0869
SF295 CTRP1 6.8088 8.3358 4.5497 0.7698
SF126 GDSC1; CTRP2 7.158 10.5604 4.6335 4.0939
NMC-G1 GDSC1; CTRP2 7.3719 9.0093 5.4676 0.7728
SNU-489 CTRP2 7.4796 9.4658 5.3299 1.12
SNU-1105 CTRP2 7.6377 8.7691 5.6759 0.1521
U-87MG ATCC GDSC1; CTRP2 7.7471 9.0422 5.6197 0.2126
GaMG CTRP2; CTRP1 7.7907 11.1553 4.7559 2.8298
DBTRG-05MG CTRP2 7.7998 9.377 4.5392 0.1091
SNU-626 CTRP2 7.893 9.3001 5.5829 0.2316
SNU-201 CTRP2 7.9315 9.144 5.6529 0.1184
KNS-81 CTRP2 8.0317 8.9956 5.738 0.0313
KALS-1 GDSC1; CTRP2 8.131 12.1436 4.5083 3.3675
ONS-76 GDSC1; CTRP2 8.1964 10.1161 5.4024 0.4757
SW1088 CTRP2 8.4542 10.0603 5.5243 0.177
T98G CTRP2 11.2965 24.1057 0.9256 12.0561
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 4.4318 5.8569 1.8599 0.3075
ETK-1 GDSC1 4.7867 7.0731 1.5531 1.1632
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-151 CTRP2; CTRP1 1.57 2.2025 1.57 41.5478
JHUEM-1 CTRP2 2.4596 3.356 2.4595 23.8827
MFE-296 CTRP2 2.7101 3.944 2.7071 22.2237
AN3-CA CTRP2 2.895 4.5195 2.8744 21.051
ESS-1 CTRP2 2.949 4.4244 2.9357 20.6665
JHUEM-7 CTRP2 2.979 5.1249 2.8978 20.698
JHUEM-3 CTRP2 3.0227 5.5828 2.8604 20.6902
HEC-1-A CTRP2 3.2258 5.1174 3.1629 18.9912
JHUEM-2 CTRP2; CTRP1 3.3642 5.2232 3.2969 18.1634
EN CTRP2 4.616 5.2423 4.6122 9.5289
MFE-319 CTRP2; CTRP1 4.8909 5.7036 4.8595 7.7914
HEC-265 CTRP2; CTRP1 6.1461 8.237 5.0316 4.0647
KLE CTRP1 6.7391 9.0305 4.2368 2.7083
HEC-6 CTRP2; CTRP1 7.8987 9.3221 5.5771 0.2398
RL95-2 GDSC1; CTRP2 7.9171 9.0742 5.6719 0.0987
EFE-184 CTRP2 7.9828 9.4982 5.5459 0.2684
HEC-59 CTRP2; CTRP1 8.0337 9.1362 5.6918 0.0628
HEC-108 CTRP2; CTRP1 8.0925 9.7536 5.4956 0.3247
HEC-251 CTRP2; CTRP1 8.4221 10.3858 5.3942 0.4024
HEC-1-B CTRP2 8.5551 9.9913 5.5844 0.0925
HEC-50B CTRP2 13.1 29.6321 -0.516 13.9605
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 7.9184 9.0727 5.6729 0.0974
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR14TKB CTRP2 0.6529 3.6716 -2.9958 2.7356
BB65-RCC GDSC1 1.5972 3.0077 1.2769 11.3079
LB2241-RCC GDSC1 1.7583 3.0145 1.4396 9.3108
TK-10 GDSC1 1.9015 2.8708 1.6494 7.0534
UO-31 CTRP2 2.5478 3.9259 2.543 23.3107
RCC10RGB GDSC1; CTRP2; CTRP1 2.6011 3.0689 2.6011 23.0142
KMRC-3 CTRP2 3.0619 4.6825 3.0365 19.955
RXF 393L GDSC1 3.0893 5.3463 1.3916 4.9767
CAL-54 CTRP2 3.1404 4.5712 3.074 13.833
LB996-RCC GDSC1 4.0397 6.3616 1.4903 2.3716
A-498 GDSC1 4.0745 5.7038 1.7739 0.8335
KMRC-2 CTRP2 4.3803 5.3651 4.3589 11.1586
ACHN CTRP2 4.4034 5.6213 4.3488 11.1189
VMRC-RCZ CTRP2 4.4228 5.5649 4.3788 10.9529
HA7-RCC GDSC1 4.4831 6.6728 1.5758 1.3481
KMRC-1 CTRP2 4.5426 4.9654 4.5425 10.0054
786-O CTRP2 4.5469 5.4156 4.369 4.2569
Caki-1 CTRP2 4.5811 5.4031 4.5664 9.7979
Caki-2 CTRP2 5.1349 7.4934 4.4705 8.6095
LB1047-RCC GDSC1 5.297 7.8466 1.4738 1.0748
OS-RC-2 GDSC1; CTRP2 7.3143 9.3273 5.3014 1.3622
TUHR4TKB CTRP2 7.3917 9.0223 5.4719 0.7456
TUHR10TKB CTRP2 7.6464 8.9001 5.6319 0.2227
BFTC-909 CTRP2 7.9062 10.3015 5.1942 1.2099
KMRC-20 CTRP2 8.1692 9.942 5.4567 0.3728
VMRC-RCW CTRP2; CTRP1 8.3967 10.1514 5.4701 0.2727
769-P CTRP2 12.1911 26.3049 0.4636 12.3501
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-C5 CTRP2; CTRP1 0.9811 2.5143 0.9802 33.7993
HCT 116 CTRP2; CTRP1 1.325 2.9935 1.322 31.5176
SNU-81 CTRP1 1.4435 3.8844 1.4091 64.4274
COLO 320 CTRP2; CTRP1 1.5278 5.4241 1.2717 31.0092
T84 CTRP2 1.5659 3.5477 1.5535 29.8778
KM12 GDSC1; CTRP2; CTRP1 1.7665 18.2759 -3.9134 40.2156
LS180 CTRP2; CTRP1 1.7991 2.4832 1.7991 40.2772
SNU-1033 CTRP2 1.9852 3.3962 1.9829 27.0504
SNU-175 CTRP1 2.4659 4.3118 2.4429 51.2872
COLO 320HSR GDSC1 2.518 3.9419 1.669 4.4813
SW948 CTRP2; CTRP1 2.5245 4.6303 2.4777 23.6818
HT-55 CTRP2; CTRP1 2.5685 3.7436 2.5669 23.2366
CL-34 CTRP1 2.6853 4.6047 2.6493 48.2591
HCT 15 CTRP2 2.7702 4.2754 2.7224 16.4058
NCI-H508 CTRP2; CTRP1 2.8301 4.4065 2.8143 21.5428
RKO GDSC1; CTRP2; CTRP1 2.8312 4.6276 2.8002 21.5868
NCI-H747 GDSC1 2.8414 5.0125 1.3811 5.7345
SNU-61 CTRP2; CTRP1 2.9421 4.0128 2.9405 20.7498
HCT 8 CTRP2; CTRP1 2.9765 3.7155 2.9764 20.5158
LS123 GDSC1; CTRP2; CTRP1 3.0629 3.9393 3.0625 19.9418
LS1034 GDSC1; CTRP2 3.1373 4.6174 3.1195 19.4271
COLO 678 CTRP2; CTRP1 3.2856 5.635 3.1366 18.9712
HCC-56 CTRP2 3.454 4.9159 3.4275 17.3467
C2BBe1 GDSC1; CTRP2; CTRP1 3.4595 5.267 3.3914 17.4527
RCM-1 [Human ESC] CTRP2; CTRP1 3.5288 4.3491 3.528 16.8424
CW-2 GDSC1; CTRP2; CTRP1 3.5683 4.8658 3.5511 16.6345
NCI-H716 GDSC1; CTRP2 3.6007 5.9099 3.1701 11.9974
CL-40 CTRP1 3.6115 4.3122 3.6112 34.9648
HT115 CTRP1 3.6851 5.4391 3.6074 34.4454
GP2d CTRP2; CTRP1 3.704 5.1444 3.6681 15.7133
HCC2998 GDSC1 3.8327 6.0908 1.4978 2.6572
SW1417 CTRP2 3.9142 5.5968 3.8247 14.4985
LoVo CTRP2; CTRP1 3.9348 5.3554 3.8881 14.2955
SNU-C1 GDSC1; CTRP2 4.1202 5.4687 4.069 12.9933
MDST8 GDSC1; CTRP2; CTRP1 4.4825 4.9225 4.4823 10.4928
SNU-C4 CTRP2; CTRP1 4.6805 5.9012 4.5946 9.4711
SW620 CTRP2; CTRP1 4.7577 11.6415 2.1207 18.9709
SNU-1040 CTRP1 5.0729 5.9003 5.0216 14.4646
SNU-503 CTRP2 5.3823 6.2406 5.2601 4.8496
SW48 CTRP2; CTRP1 5.507 8.09 4.5453 7.4214
SW480 CTRP1 6.1585 11.0649 3.6384 20.1074
DLD-1 CTRP2; CTRP1 6.992 8.5574 5.4621 1.1138
OUMS-23 CTRP2 7.3709 8.7429 5.5753 0.4696
LS411N GDSC1; CTRP2; CTRP1 7.4784 9.0175 5.5151 0.5666
SW403 CTRP1 7.6969 11.1763 3.8182 3.8652
COLO205 CTRP2; CTRP1 7.7527 8.9961 5.6385 0.1799
SW1116 CTRP2 7.9771 9.3312 5.604 0.1747
LS513 GDSC1; CTRP2; CTRP1 8.0312 9.1611 5.6826 0.0712
SK-CO-1 CTRP2; CTRP1 8.1361 9.7867 5.5008 0.2999
CL-11 GDSC1; CTRP2 8.4202 10.0935 5.4999 0.2193
SNU-407 CTRP2 8.6776 10.443 5.4725 0.1982
SNU-C2A CTRP2; CTRP1 9.1737 11.2329 5.3783 0.2176
HT-29 CTRP2; CTRP1 11.7165 27.1324 -0.218 14.8498
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 4.8434 6.6846 1.7207 0.5044
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 CTRP2; CTRP1 1.858 3.1492 1.858 39.9501
JHH-2 CTRP2 1.8594 3.5276 1.8533 27.9016
SNU-423 CTRP2 2.7458 5.074 2.6555 22.283
Hep-G2 CTRP2; CTRP1 2.9078 28.355 -7.813 40.9983
JHH-5 CTRP2 2.9859 5.1993 2.8935 20.6908
HLF CTRP2 3.29 5.4129 3.1843 18.7121
JHH-4 CTRP2 3.7243 4.9599 3.7064 15.5169
SNU-449 CTRP2; CTRP1 4.3323 5.2741 4.3168 11.4583
PLC/PRF/5 CTRP2 4.4119 5.3273 4.3957 10.9305
SK-HEP-1 CTRP2 4.4796 4.8808 4.4795 10.4254
SNU-387 CTRP2 4.5579 5.6983 4.5019 10.0948
JHH-1 CTRP2 4.6147 5.0394 4.6145 9.5255
HuH-1 CTRP2 5.3434 6.6746 5.0478 5.7737
SNU-475 CTRP2 5.4457 5.9504 5.4141 4.0974
JHH-6 CTRP2; CTRP1 5.6547 5.928 5.6443 2.6313
SNU-761 CTRP2 5.7015 6.5747 5.4583 3.2166
SNU-182 CTRP2 5.958 7.5585 5.2142 3.6598
SNU-878 CTRP2 7.1028 9.4819 5.1072 2.3039
HuH-6 CTRP2 7.2557 11.0169 4.4808 4.5682
Hep 3B2.1-7 CTRP2 7.9051 9.7391 5.4221 0.5684
Li-7 CTRP2 8.2636 10.4371 5.3076 0.6646
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 183 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COR-L47 CTRP2 0.068 3.7278 -0.0216 40.0693
SCLC-21H CTRP1 0.1723 2.3588 0.172 98.0127
LC-1F CTRP2 0.2073 13.6416 -8.0242 28.8453
NCI-H1694 GDSC1; CTRP2; CTRP1 0.3135 1.7688 0.3133 38.2403
NCI-H1105 CTRP2; CTRP1 0.656 2.2714 0.6551 35.963
COR-L51 CTRP2; CTRP1 1.3657 2.6313 1.3657 42.6812
COR-L23 CTRP1 1.4398 3.2321 1.4342 65.4142
COR-L279 CTRP2; CTRP1 1.5389 2.7446 1.5386 30.0172
NCI-H2171 GDSC1; CTRP2 1.5638 2.8488 1.5607 24.8545
NCI-H1963 GDSC1; CTRP1 1.5763 2.4251 1.5763 50.7739
NCI-H720 GDSC1 1.5943 2.3045 1.5326 9.4995
NCI-H3255 CTRP1 1.5945 3.26 1.5903 63.4323
NCI-H524 GDSC1 1.6156 4.0538 0.8146 14.7008
DMS 53 CTRP2 1.6779 4.1725 1.6303 29.2498
NCI-H2141 GDSC1; CTRP2; CTRP1 1.694 3.2502 1.6939 40.8602
NCI-H1341 CTRP2 1.7205 3.2094 1.7105 23.7608
NCI-H810 CTRP2; CTRP1 1.7226 2.9333 1.7222 28.7939
NCI-H1876 GDSC1; CTRP1 1.8112 3.2869 1.8088 36.2008
NCI-H2081 GDSC1; CTRP2; CTRP1 1.8238 3.399 1.8199 28.2006
NCI-H1436 GDSC1 1.9062 2.5477 1.7914 5.9839
NCI-H1304 GDSC1 1.952 2.93 1.6731 6.6359
COR-L95 GDSC1; CTRP2 2.0224 3.2704 2.0214 26.7984
NCI-H522 CTRP2; CTRP1 2.1221 3.8497 2.1115 26.1662
NCI-H64 GDSC1 2.1905 3.9496 1.3961 7.7916
NCI-H1836 GDSC1; CTRP1 2.2172 3.5956 2.2145 32.7431
NCI-H847 GDSC1 2.2297 3.0815 1.8628 3.9699
NCI-H2196 GDSC1; CTRP2 2.2989 4.2969 2.2142 19.9057
NCI-H1781 CTRP1 2.3786 3.9377 2.3707 52.5388
NCI-H748 GDSC1 2.39 5.0905 0.9939 10.2077
NCI-H1092 GDSC1; CTRP2 2.3975 3.4642 2.3933 18.9077
DMS 454 CTRP2 2.425 4.1719 2.4084 24.1687
NCI-H345 GDSC1 2.4411 3.2686 1.9438 2.5773
Lu-134-A GDSC1 2.4741 3.884 1.6638 4.6647
Calu-1 CTRP2 2.5549 2.937 2.5549 23.2472
NCI-H1563 CTRP2 2.6043 4.1775 2.5927 22.9574
RERF-LC-Ad2 CTRP2 2.6468 3.3826 2.6463 17.1152
DV-90 CTRP2; CTRP1 2.6757 4.273 2.6617 22.4893
NCI-H526 GDSC1 2.6773 4.2816 1.6201 4.373
NCI-H596 CTRP1 2.7121 3.6858 2.7116 47.8133
NCI-H2342 CTRP2; CTRP1 2.8564 4.6716 2.8229 21.4275
HCC4006 CTRP2; CTRP1 2.895 4.2606 2.8874 21.0835
LB647-SCLC GDSC1 2.9348 5.4827 1.2186 6.7082
HCC1359 CTRP1 2.9912 4.7075 2.961 43.97
NCI-H1770 GDSC1 3.0264 4.9216 1.5519 3.9453
HOP-92 CTRP2 3.0305 4.3108 3.0239 20.1008
IST-SL2 GDSC1 3.0744 5.2481 1.4284 4.7404
NCI-H841 CTRP2; CTRP1 3.1378 4.5642 3.1235 19.4899
NCI-H187 GDSC1 3.1513 5.4281 1.3937 4.8028
DMS 273 CTRP2; CTRP1 3.2639 4.7731 3.2403 18.6036
NCI-H250 GDSC1 3.2734 5.2074 1.5739 3.2135
COLO 699 CTRP2; CTRP1 3.2832 4.1344 3.2826 18.4761
Sq-1 CTRP2; CTRP1 3.359 4.3406 3.3568 17.9771
CPC-N GDSC1 3.3653 5.1137 1.6698 2.3736
NCI-H1395 CTRP2 3.5238 6.2633 3.2308 17.8256
HCC2935 CTRP2; CTRP1 3.5284 4.8496 3.5108 16.9013
NCI-H1703 CTRP2 3.5455 6.9144 2.6854 14.1902
NCI-H128 GDSC1 3.5784 9.2833 -0.1753 14.679
HCC2108 CTRP2; CTRP1 3.585 4.5092 3.5826 16.4737
DMS 114 GDSC1; CTRP2 3.5893 4.8755 3.5719 16.4144
Lu-139 GDSC1 3.5905 5.7475 1.5152 2.9769
NCI-H2135 GDSC1 3.6959 5.2878 1.7673 1.2666
NCI-H441 CTRP1 3.7066 5.5923 3.6024 34.317
SBC-1 GDSC1 3.7355 7.3249 0.8776 7.1097
IST-SL1 GDSC1 3.7745 5.9551 1.5254 2.5814
NCI-H1869 GDSC1; CTRP2 3.7935 5.2803 3.7466 15.1547
HCC1438 CTRP2 3.8201 5.5138 3.7385 15.0976
NCI-H2029 CTRP2; CTRP1 3.8229 5.5102 3.7422 15.0758
HCC15 CTRP2; CTRP1 3.8334 6.4872 3.501 15.9939
NCI-H23 GDSC1; CTRP2; CTRP1 3.8374 5.1588 3.8075 14.804
SK-MES-1 CTRP2 3.863 5.6089 3.7669 14.8625
NCI-H1155 GDSC1; CTRP2 3.8948 5.1814 3.8657 14.4188
LUDLU-1 CTRP2 3.9051 5.8227 3.7663 14.7332
COR-L105 CTRP2 3.9324 5.3185 3.8895 14.2157
VMRC-LCD CTRP2; CTRP1 3.9762 5.197 3.95 13.8669
Ms-1 GDSC1 4.0002 5.948 1.6431 1.5542
COLO 668 GDSC1; CTRP2; CTRP1 4.028 5.4309 3.9759 13.6109
NCI-H69 GDSC1 4.0387 6.2713 1.5279 2.1506
HCC827 CTRP2; CTRP1 4.0773 5.36 4.0393 13.3175
HCC1195 CTRP2; CTRP1 4.0939 4.8119 4.0923 13.0837
NCI-H510A GDSC1 4.2006 5.9257 1.7427 0.858
NCI-H2073 CTRP1 4.2286 5.4697 4.186 26.456
Lu-165 GDSC1 4.3169 5.902 1.7995 0.5507
T3M-10 CTRP2; CTRP1 4.3637 6.6215 4.0296 12.4845
COR-L88 GDSC1; CTRP2; CTRP1 4.3886 6.5346 4.0832 12.1278
NCI-H1339 CTRP2 4.4118 4.9907 4.4107 10.8804
NCI-H1648 GDSC1 4.414 6.7473 1.5143 1.7318
NCI-H1915 CTRP2; CTRP1 4.4169 5.7963 4.3294 11.1442
NCI-H1693 CTRP2 4.4634 5.8028 4.3784 10.8259
NCI-H322M GDSC1 4.4719 6.5669 1.6123 1.1886
IA-LM CTRP2 4.4779 5.5187 4.4444 10.5496
NCI-H838 CTRP2 4.5059 5.0042 4.4672 3.9874
NCI-H211 GDSC1; CTRP2 4.5455 5.6942 4.4892 10.1782
LC-2/ad GDSC1 4.5486 6.6228 1.624 1.0657
NCI-H2122 CTRP2; CTRP1 4.5641 16.8026 -0.6044 27.8728
ChaGo-K-1 CTRP2; CTRP1 4.5994 6.307 4.3886 10.3764
Lu-65 GDSC1; CTRP2; CTRP1 4.6239 15.7393 -0.0324 26.2024
SBC-5 CTRP2 4.7454 7.738 3.9673 11.6106
NCI-H1048 CTRP1 4.7607 7.2714 3.6953 13.5357
NCI-H1184 CTRP2 4.8334 8.1181 2.6549 5.4326
RERF-LC-MS CTRP2 4.9021 5.6516 4.8789 7.6888
NCI-H2087 CTRP2 4.9432 6.201 4.7965 7.8563
NCI-H209 GDSC1 4.9469 6.7585 1.7335 0.4184
Lu-99 CTRP2; CTRP1 4.9879 7.3243 4.3986 9.2698
NCI-H1838 GDSC1 5.0569 6.8318 1.7485 0.3361
NCI-H2227 GDSC1 5.0586 6.7363 1.7821 0.2614
SK-LU-1 CTRP2; CTRP1 5.0929 6.7136 4.7744 7.6028
CAL-12T CTRP2; CTRP1 5.1185 9.3515 3.5755 12.3872
NCI-H322 CTRP2 5.1829 6.1191 5.0829 6.092
NCI-H2170 CTRP2 5.2163 6.0641 5.1352 5.8012
NCI-H647 CTRP2 5.219 6.3926 5.0293 6.1864
NCI-H1623 CTRP2 5.2241 8.7715 3.9488 10.5294
RERF-LC-A1 CTRP2 5.2712 8.2318 4.2545 9.1618
NCI-H1944 CTRP2; CTRP1 5.308 6.5359 5.0683 5.7894
NCI-H2030 CTRP2; CTRP1 5.3171 5.9894 5.2672 5.1101
NCI-H1930 CTRP1 5.3185 7.7005 3.9477 8.9719
NCI-H1651 CTRP2 5.3247 7.871 4.4789 8.115
KNS-62 CTRP2; CTRP1 5.444 5.9916 5.4028 4.1427
HOP-62 GDSC1; CTRP2 5.4717 6.1874 5.3752 4.1606
NCI-H1793 CTRP2; CTRP1 5.5339 6.133 5.4608 3.6608
NCI-H1568 CTRP2; CTRP1 5.5438 7.3758 4.2754 2.6402
HCC1833 CTRP2; CTRP1 5.6053 6.9841 5.1796 4.6712
NCI-H2172 CTRP1 5.7562 8.1107 4.771 12.8957
NCI-H2106 CTRP2 5.7862 7.2001 5.2394 3.9173
EKVX GDSC1; CTRP2 5.8392 9.2377 4.2736 7.8482
NCI-H520 CTRP2 5.9015 10.7134 3.5898 10.5804
NCI-H2023 CTRP2; CTRP1 6.0395 6.9206 5.6118 1.9155
LC-1/sq-SF CTRP2; CTRP1 6.133 7.4438 5.4171 2.4705
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 6.1399 8.5955 4.8475 4.8497
NCI-H2286 CTRP1 6.1477 8.3097 4.2263 4.0118
NCI-H2110 CTRP2; CTRP1 6.2749 12.4743 3.0294 12.2267
Calu-3 CTRP2; CTRP1 6.3727 8.5812 5.0381 3.6371
NCI-H1581 GDSC1; CTRP2 6.4225 9.1452 4.7967 4.5583
NCI-H1435 CTRP2; CTRP1 6.4316 8.0916 4.4762 0.8113
BEN CTRP2; CTRP1 6.7165 11.3647 3.9215 7.6986
NCI-H82 GDSC1; CTRP1 6.8273 14.7522 1.5954 15.0162
NCI-H1437 CTRP1 6.9508 9.7087 4.057 3.5722
LXF 289 GDSC1; CTRP2; CTRP1 7.0052 8.9749 4.3878 0.6902
NCI-H1975 GDSC1; CTRP1 7.0455 9.6062 4.1497 1.8132
RERF-LC-KJ CTRP1 7.1169 9.1117 4.3837 1.2782
MOR/CPR CTRP2 7.362 17.2934 1.4767 16.0004
HCC33 GDSC1; CTRP1 7.4248 13.4658 2.6257 8.8149
NCI-H2444 CTRP2 7.4269 8.4708 5.7023 0.1679
NCI-H2126 CTRP2; CTRP1 7.4693 8.5893 4.7033 0.032
NCI-H460 CTRP2; CTRP1 7.4902 9.4759 5.3442 1.1227
HCC44 CTRP2; CTRP1 7.6955 10.0239 5.2038 1.3489
NCI-H226 GDSC1; CTRP2 7.8439 9.0041 5.6697 0.1146
NCI-H1573 CTRP2; CTRP1 7.8593 9.6114 5.4518 0.5193
LCLC-103H CTRP2; CTRP1 7.9667 9.0243 5.7064 0.0586
NCI-H358 CTRP2; CTRP1 8.0132 10.6254 5.112 1.3836
SHP-77 GDSC1; CTRP2; CTRP1 8.0584 9.3707 5.6203 0.1342
NCI-H2009 CTRP2; CTRP1 8.061 10.0787 5.3582 0.6452
NCI-H650 CTRP2; CTRP1 8.1143 9.5162 5.5898 0.1626
NCI-H1373 CTRP2; CTRP1 8.1999 9.8217 5.5131 0.2583
NCI-H661 CTRP2; CTRP1 8.2628 12.8414 4.2685 4.1098
HCC95 CTRP2 8.2911 9.9351 5.5074 0.2415
NCI-H1755 CTRP2; CTRP1 8.3567 10.0418 5.5084 0.2489
LCLC-97TM1 CTRP2; CTRP1 8.3724 10.3976 5.3694 0.4726
NCI-H2085 CTRP2 8.3845 10.1551 5.464 0.2865
HCC1588 CTRP2 8.4007 10.0885 5.4943 0.2328
NCI-H1666 GDSC1; CTRP2; CTRP1 8.4107 10.3849 5.3899 0.4152
NCI-H446 GDSC1; CTRP2 8.4158 10.1919 5.4629 0.2791
DMS 79 GDSC1; CTRP2 8.4265 10.0649 5.5124 0.1995
HCC366 CTRP2 8.4461 9.9823 5.5486 0.1477
HCC1171 CTRP2 8.4557 10.0753 5.5196 0.183
Calu-6 GDSC1; CTRP2; CTRP1 8.4568 14.1604 3.7774 5.7338
EBC-1 CTRP2; CTRP1 8.4724 9.8944 5.5882 0.1001
EPLC-272H CTRP2; CTRP1 8.5074 10.3306 5.4482 0.277
NCI-H1792 CTRP2; CTRP1 8.5278 9.9751 5.5803 0.1
PC-14 CTRP2 8.5528 10.3909 5.4439 0.2712
HCC78 CTRP2; CTRP1 8.562 15.3528 3.284 7.4776
LOU-NH91 CTRP2 8.5993 9.9531 5.6125 0.0644
NCI-H1299 GDSC1; CTRP2; CTRP1 8.7234 10.3613 5.5175 0.1347
NCI-H1650 GDSC1; CTRP2 8.7375 10.4693 5.4853 0.1695
NCI-H2228 CTRP2 8.7471 10.4454 5.497 0.1537
SW1271 CTRP2 8.7671 10.7901 5.3826 0.3108
HCC2279 CTRP2 8.7796 10.5113 5.486 0.1608
NCI-H1355 GDSC1; CTRP2; CTRP1 8.8535 10.7062 5.445 0.1972
NCI-H727 CTRP2; CTRP1 8.9572 10.3642 5.5972 0.0449
NCI-H2405 CTRP2; CTRP1 8.966 11.2143 5.3061 0.3814
NCI-H889 CTRP2 8.998 18.9891 1.8375 12.1523
A-549 CTRP2; CTRP1 9.1831 11.0677 5.4389 0.1453
SW1573 CTRP2 9.2749 11.605 5.2844 0.3281
Hs 888.Lu CTRP2 4.4266 5.6996 4.3596 11.0077
⏷ Show the Full List of 183 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 2.7735 4.651 1.5089 4.949
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 1.4689 2.5751 1.4688 30.4832
H-STS CTRP2 1.4733 2.1417 1.4733 25.4891
SYO-1 CTRP2 3.5747 4.8479 3.5586 16.5077
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 2.5718 3.2485 2.5718 23.135
OVKATE CTRP1 0.0327 2.5525 0.0319 97.4218
OVK18 CTRP2; CTRP1 1.2477 2.4391 1.2476 32.0224
OVCAR-8 CTRP2; CTRP1 1.5674 2.3815 1.5674 41.5623
OVCAR-4 GDSC1; CTRP2; CTRP1 1.9401 2.9535 1.9401 39.4947
RMG-I CTRP2; CTRP1 1.9931 4.7121 1.9038 27.3621
COV434 CTRP2; CTRP1 2.08 3.6947 2.0735 26.5039
TOV-21G CTRP2 2.1054 3.5221 2.1026 26.2514
ES-2 GDSC1 2.2115 3.1013 1.8367 4.2463
EFO-27 CTRP2; CTRP1 2.2616 2.9723 2.2616 25.2737
OC 314 CTRP2 2.4001 2.9158 2.4001 24.2791
RMUG-S CTRP1 2.6124 4.7595 2.5566 49.277
JHOC-5 CTRP2; CTRP1 2.7609 3.7806 2.7601 21.953
IGROV-1 CTRP2; CTRP1 2.8554 4.6066 2.8547 34.4185
SNU-840 CTRP2; CTRP1 2.9568 4.0029 2.9554 20.6512
OV-90 CTRP2; CTRP1 2.9703 4.8197 2.9285 20.6975
TYK-nu CTRP2; CTRP1 2.9934 5.1839 2.9053 20.7026
JHOM-1 CTRP2; CTRP1 3.3411 5.1807 3.2783 18.3018
COV644 CTRP2; CTRP1 3.5084 4.5302 3.5046 16.9882
TOV-112D CTRP2 3.5793 5.4533 3.4895 16.7299
JHOS-2 CTRP2 3.6018 7.6048 2.4266 15.1425
OVCAR-5 CTRP2 3.8638 5.1095 3.8401 14.6073
A2780 CTRP2; CTRP1 4.1734 6.3733 4.1583 27.1465
COV362 CTRP2; CTRP1 4.4735 5.4138 4.4529 10.6214
OV56 CTRP2 4.507 4.9264 4.5069 10.2429
EFO-21 CTRP2; CTRP1 4.6411 5.1206 4.6404 9.3512
Caov-3 CTRP2; CTRP1 4.6501 5.1974 4.6483 9.3827
OV7 CTRP2; CTRP1 4.6825 5.4905 4.6655 9.2183
OAW42 CTRP2; CTRP1 4.8577 5.8207 4.8045 8.1774
SNU-119 CTRP2 6.54 8.2411 5.3266 2.184
OAW28 CTRP2 6.5948 9.587 4.7083 4.639
JHOS-4 CTRP1 6.616 8.9674 4.199 3.2018
ES2 CTRP2 6.7653 8.3849 5.4065 1.5675
COV318 CTRP1 6.8344 7.8783 4.7239 0.1598
OVMANA CTRP1 7.1448 8.3704 4.6657 0.1871
OVISE CTRP2 7.5292 9.5657 5.313 1.1334
FU-OV-1 CTRP2 7.6446 9.2605 5.494 0.5268
HEY A8 CTRP2; CTRP1 7.7107 9.5222 5.4201 0.6834
SNU-8 CTRP2 7.9654 8.9951 5.7157 0.0514
ONCO-DG-1 CTRP2 8.0215 9.4759 5.5691 0.217
SK-OV-3 CTRP2; CTRP1 8.1272 9.5107 5.5965 0.1508
DOV13 CTRP2 8.2625 11.4223 4.9015 1.8568
OVTOKO CTRP2 8.3562 10.1982 5.4371 0.3436
OVSAHO CTRP2 8.5721 10.0837 5.5589 0.1148
Kuramochi GDSC1; CTRP2 8.5793 10.3495 5.4688 0.226
MCAS CTRP2 12.3133 25.426 0.9459 10.8165
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 2.5942 3.0004 2.5942 22.9854
Aska-SS CTRP2 2.6802 3.1865 2.6802 22.413
TE 441.T GDSC1; CTRP2 1.7774 2.8084 1.7773 28.4279
GCT CTRP2 1.9367 3.6604 1.9284 27.3937
VA-ES-BJ GDSC1 2.0812 3.0965 1.7194 5.7021
TTC-709 CTRP2 2.1982 2.8847 2.1981 25.6242
A-204 CTRP2 2.2073 3.2936 2.2069 25.5648
RD CTRP2 2.2438 5.8328 1.9525 26.3222
TE 617.T CTRP2 2.3013 4.6914 2.1392 20.1791
SW872 GDSC1 2.3809 3.4852 1.7887 3.9966
KYM-1 CTRP2 2.4036 3.3885 2.4034 24.2562
G-402 CTRP2 2.4093 4.0277 2.3988 24.2529
G-401 CTRP2; CTRP1 2.4806 4.2011 2.4643 23.797
BT-12 CTRP2 2.6388 2.9325 2.6388 22.6885
MFH-ino GDSC1 2.6991 5.3379 1.1156 8.2184
RKN CTRP2; CTRP1 2.7271 3.6568 2.7271 35.1282
SW684 GDSC1 3.106 4.5446 1.776 2.1596
SW982 CTRP2 3.1427 4.4713 3.1328 19.3648
Hs 729.T CTRP2 3.6354 5.3916 3.5606 16.304
Tm87-16 CTRP2 4.2371 5.3865 4.2051 12.1487
HT-1080 CTRP2; CTRP1 4.4019 5.9151 4.2877 11.4243
MES-SA CTRP2 4.4535 4.8608 4.4534 10.5989
SK-LMS-1 GDSC1; CTRP2 4.4998 5.1914 4.4951 10.306
EW-8 GDSC1 4.6465 6.0994 1.8538 0.2422
BT-16 CTRP2 5.8392 6.6656 5.5497 2.5124
SK-UT-1 GDSC1; CTRP2 7.3293 16.6421 1.7746 15.0178
Rh41 CTRP2 7.9802 9.537 5.5306 0.2976
Rh18 CTRP2 8.1669 9.5165 5.609 0.1272
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 3.6821 5.4669 3.4241 10.7171
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 GDSC1; CTRP2 4.3547 6.6448 4.0075 12.5097
JL-1 CTRP2 4.5136 4.924 4.5135 10.1988
IST-Mes1 GDSC1; CTRP2 4.6055 5.6329 4.5643 9.7262
MSTO-211H GDSC1; CTRP2; CTRP1 7.0982 10.1601 4.7847 3.573
ACC-MESO-1 CTRP2 8.2645 9.4512 5.6656 0.0585
NCI-H28 CTRP2; CTRP1 8.4268 10.4074 5.3881 0.4127
NCI-H2052 CTRP2; CTRP1 8.7173 10.2318 5.5595 0.0941
NCI-H2452 CTRP2 8.9465 10.8004 5.4461 0.1775
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; CTRP2 2.2564 5.0506 2.1332 25.6555
LNCaP clone FGC GDSC1; CTRP2 4.1215 5.6011 4.0482 13.0616
DU145 CTRP2 4.2575 6.9273 3.798 13.579
PaCa-3 CTRP2; CTRP1 4.6191 5.2219 4.6161 9.5056
22Rv1 CTRP2 8.8389 10.7237 5.4335 0.2157
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; CTRP2 4.4397 5.5327 4.4016 10.8201
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 2.6535 4.5493 1.471 5.6008
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GCIY GDSC1 1.3024 2.4509 1.1716 13.6125
RF-48 GDSC1 1.5149 2.8978 1.2371 12.0135
NCC-StC-K140 CTRP2 1.643 3.6248 1.6294 29.3683
HGC-27 CTRP2 2.3446 3.0202 2.3446 24.6485
SNU-216 CTRP2 2.5619 3.3661 2.5618 23.2011
SNU-16 GDSC1; CTRP2 2.9869 4.7495 2.9521 20.4866
SNU-601 CTRP2 3.28 4.7757 3.2569 18.4944
SNU-5 GDSC1 3.6469 5.3904 1.7005 1.7108
MKN7 CTRP2; CTRP1 3.6954 4.5599 3.6934 15.6561
Hs 746.T CTRP2 3.747 5.1457 3.7134 15.4192
SCH GDSC1 4.1451 5.1536 1.9995 0.1071
HuG1-N CTRP2 4.2617 5.7429 4.1722 12.1846
HSC-39 GDSC1 4.2841 5.6716 1.8703 0.3453
SNU-1 GDSC1; CTRP2 4.4749 5.5888 4.431 10.6058
KATO III CTRP2 4.4944 5.5377 4.263 4.8513
LMSU CTRP2 4.5071 5.5993 4.4639 10.3889
ECC10 CTRP2 4.6828 6.0724 4.5507 9.5343
IM95 CTRP2 4.695 5.9908 4.586 9.3697
SH-10-TC CTRP2; CTRP1 4.9344 5.7528 4.8984 7.5176
AGS CTRP2; CTRP1 5.5577 6.3292 5.5577 19.4244
NCI-N87 GDSC1 5.6541 16.8877 -2.4058 20.1954
KE-39 CTRP2 5.7521 9.9846 3.8257 9.8998
MKN1 CTRP2 6.7815 9.1249 5.0668 2.8855
GSU CTRP2 6.9232 7.5926 5.8248 0.1103
GSS CTRP2 7.5852 9.2822 5.4582 0.6563
ECC12 GDSC1; CTRP2 7.747 8.8474 5.689 0.1095
NUGC-4 CTRP2; CTRP1 7.8314 9.6261 5.4336 0.5785
MKN74 CTRP2; CTRP1 7.8727 13.0419 3.927 5.9161
SNU-620 CTRP2 7.9327 9.0559 5.6838 0.0837
Fu97 CTRP2; CTRP1 8.1405 9.7318 5.5226 0.2599
NUGC-3 CTRP2 8.1517 9.5228 5.6013 0.1396
SNU-719 CTRP2 8.2424 9.9587 5.4799 0.3031
23132/87 CTRP2 8.4836 9.9452 5.5749 0.1118
MKN45 CTRP2 9.4168 22.0255 0.66 15.3705
SNU-685 CTRP2 3.589 5.1163 3.4359 10.9645
SNG-M CTRP2; CTRP1 8.1089 15.0528 3.123 8.7258
SNU-1077 CTRP2 8.5725 9.9873 5.5918 0.0837
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FTC-238 CTRP2 2.0024 3.4749 1.9992 26.939
K5 GDSC1 2.3879 3.6472 1.7134 4.5652
FTC-133 CTRP2 4.4017 5.5468 4.3589 11.0894
TT2609-C02 CTRP2 4.4445 5.7605 4.3669 10.9258
SW579 CTRP2 4.4727 4.8722 4.4727 10.4709
8505C CTRP2 5.4362 7.92 4.5616 7.5152
ML-1 [Human leukemia] CTRP2 6.646 8.1735 5.4297 1.6271
B-CPAP CTRP2 7.8339 9.1115 5.6281 0.1744
CAL-62 CTRP2 8.1239 9.3769 5.6417 0.0978
8305C CTRP2 8.1402 9.6469 5.5531 0.2101
CGTH-W-1 GDSC1; CTRP2 8.1765 9.2994 5.6862 0.0521
TT CTRP2 8.289 9.6784 5.5971 0.1194
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB30-HNC GDSC1 2.0073 3.5613 1.4239 8.3106
SCC-9 CTRP2; CTRP1 2.5307 3.496 2.5307 36.218
SCC-4 CTRP2 2.6943 3.7484 2.6934 22.322
BICR 6 CTRP2 2.9389 3.7378 2.9388 20.6897
PE/CA-PJ49 CTRP2 4.1817 5.4596 3.9641 7.0066
BICR 16 CTRP2 4.2011 10.6289 2.0797 20.3856
CAL-33 CTRP2 4.2351 6.2517 4.0096 12.8507
HSC-2 CTRP2; CTRP1 4.3511 5.4948 4.3124 11.4121
PE/CA-PJ34 (clone C12) CTRP2 4.3808 5.5538 4.3354 11.2376
BB49-HNC GDSC1 4.4687 6.3546 1.6925 0.8453
FaDu CTRP2 4.4697 4.9315 4.4695 10.4915
CAL-27 CTRP2 4.4834 5.8729 4.3844 10.7421
PE/CA-PJ41 (clone D2) CTRP2 4.5305 5.0904 4.5291 10.0905
BICR 31 CTRP2 4.5897 5.7954 4.5172 9.9411
BICR 56 CTRP2 4.6008 5.4859 4.579 9.6913
PE/CA-PJ15 CTRP2 4.6666 5.4827 4.6488 9.2389
LB771-HNC GDSC1 4.7012 6.7602 1.6361 0.8897
BICR 22 CTRP2 4.7469 5.3145 4.7436 8.6552
BICR 18 CTRP2 4.7924 5.6205 4.7661 8.43
SNU-1041 CTRP2 7.1525 8.7748 5.4546 0.99
HSC-3 CTRP2 7.7207 9.0202 5.6173 0.2249
SNU-1076 CTRP2 7.7705 8.9096 5.6759 0.1215
YD-8 CTRP2 8.0834 9.6972 5.5128 0.2957
Detroit 562 CTRP2 8.1131 10.2993 5.2944 0.781
BHY CTRP2 8.1956 9.8238 5.5107 0.2636
HSC-4 CTRP2 8.2309 9.7318 5.5571 0.1817
SNU-1066 CTRP2 8.4075 9.9487 5.5462 0.1582
SCC-25 CTRP2 8.7112 10.3655 5.5117 0.1432
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-BLC1 CTRP2 2.5064 4.1275 2.4943 23.6114
HT-1197 CTRP2 2.7743 3.8645 2.773 21.7902
647V CTRP2 3.0774 5.0543 3.0132 19.9843
KMBC-2 CTRP2; CTRP1 3.4477 4.9979 3.4129 17.4169
T24 CTRP2 4.4896 5.5301 4.4554 10.4742
SCaBER CTRP2 4.5193 5.7047 4.4589 10.3673
UM-UC-1 CTRP2 4.6446 5.2228 4.642 9.3345
J82 CTRP2 4.817 8.2503 3.8044 12.0859
BC-3C CTRP2 5.2518 6.0689 5.1726 5.558
CAL-29 CTRP2 6.2536 8.8858 4.794 4.8657
253J CTRP2 6.6277 8.1918 5.4092 1.7317
BFTC-905 CTRP2 6.9466 10.8726 4.3347 5.6194
RT-112 CTRP2 7.0149 8.3485 4.612 0.1654
TCCSUP CTRP2 7.0668 9.7813 4.9438 2.9848
639V CTRP2 7.404 8.5871 5.65 0.2763
RT-4 CTRP2; CTRP1 7.4418 8.8946 4.5916 0.1266
UM-UC-3 CTRP2; CTRP1 8.0011 9.6044 5.5141 0.3218
VM-CUB-1 CTRP2 8.128 9.8448 5.4761 0.3497
JMSU-1 CTRP2 8.3803 9.5301 5.6787 0.0399
HT-1376 CTRP2; CTRP1 8.6085 10.7613 5.3301 0.4601
5637 CTRP2; CTRP1 9.1292 10.7332 5.5331 0.0706
KU-19-19 CTRP2 12.4875 30.0322 -1.0985 16.1227
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KGN GDSC1 1.7625 7.1309 -0.5633 23.4457
NEC8 GDSC1 1.7796 2.5233 1.665 7.5553
NT2-D1 GDSC1 2.3463 3.5367 1.7348 4.5432
SW962 GDSC1 2.4373 3.7636 1.6949 4.543
NCC-IT GDSC1 2.7055 4.3634 1.6005 4.4418
SW954 GDSC1 2.7587 4.4656 1.5887 4.3797
LB831-BLC GDSC1 3.8916 5.7581 1.6687 1.5538
OMC-1 [Human cervical carcinoma] GDSC1 4.3628 6.2254 1.697 0.9136
JAR GDSC1 4.3857 6.1399 1.739 0.7255
DSH1 GDSC1 4.7868 6.3217 1.8275 0.2527
TC-YIK GDSC1 4.8972 6.8257 1.6905 0.5683
HeLa CTRP2 4.9971 5.8415 4.6058 2.0754
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug

References

1 The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase. Chem Biol. 2001 Aug;8(8):759-66.
2 Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity. J Exp Med. 2005 Jan 3;201(1):105-15.