General Information of This Drug (ID: DMNKG1Z)

Drug Name
Atenolol   DMNKG1Z
Synonyms
Aircrit; Alinor; Altol; Anselol; Antipressan; Atcardil; Atecard; Atehexal; Atenblock; Atendol; Atenet; Ateni; Atenil; Atenol; Atenolin; Atenololum; Atenomel; Atereal; Aterol; Betablok; Betacard; Betasyn; Blocotenol; Blokium; Cardaxen; Cardiopress; Corotenol; Cuxanorm; Duraatenolol; Duratenol; Evitocor; Farnormin; Hipres; Hypoten; Ibinolo; Internolol; Jenatenol; Juvental; Loten; Lotenal; Myocord; Neatenol; Normalol; Normiten; Noten; Oraday; Ormidol; Panapres; Plenacor; Premorine; Prenolol; Prenormine; Prinorm; Selobloc; Serten; Servitenol; Stermin; Tenidon; Tenobloc; Tenoblock; Tenolol; Tenoprin; Tenormin; Tenormine; Tensimin; Tensotin; Tredol; Unibloc; Uniloc; Vascoten; Vericordin; Wesipin; Xaten; Atenol AL; Atenol Atid; Atenol Cophar; Atenol Fecofar; Atenol GNR; Atenol Gador; Atenol Genericon; Atenol Heumann; Atenol MSD; Atenol NM Pharma; Atenol Nordic; Atenol PB; Atenol Quesada; Atenol Stada; Atenol Tika; Atenol Trom; Atenol acis; Atenol ct; Atenol von ct; Betatop Ge; Scheinpharm Atenol; Seles beta; Tenormine [French]; A 7655; Atenol 1A pharma; Apo-Atenolol; Atenol-Mepha; Atenol-Wolff; Atenol-ratiopharm; Atenololum [INN-Latin]; Felo-Bits; Lo-ten; Teno-basan; Tenormin (TN); Atenolol (JP15/USP/INN); Atenolol [USAN:INN:BAN:JAN]; Acetamide,2-(p-(2-hydroxy-3-(isopropylamino)propoxy)phenyl); (+-)-4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetamide; (+-)-Atenolol; (+/-)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide; (1)-2-(4-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide; (inverted question mark)-Atenolol; 1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol; 2-(4-(2-Hydroxy-3-isopropylaminopropoxy)phenyl)acetamid; 2-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide; 2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide; 2-[4-(2-Hydroxy-3-isopropylaminopropoxy)phenyl]acetamide; 2-[4-({2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)phenyl]acetamide; 2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide; 2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide; 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide; 4-[2'-Hydroxy-3'-(isopropylamino)propoxy]phenylacetamide; 4-[2-Hydroxy-3-(isopropylamino)-propoxy]phenylacetamide
Indication
Disease Entry ICD 11 Status REF
Angina pectoris BA40 Approved [1]
Hypertension BA00-BA04 Approved [2]
Malignant essential hypertension BA00 Approved [1]
Myocardial infarction BA41-BA43 Approved [1]
Therapeutic Class
Antihypertensive Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

50 Investigative Drug Combination(s) Consisting of This drug
Normalized Drug Combination Synergy Score
Synergy scores were normalized using Min-Max Scaling to facilitate visual comparisons.
DrugCom Name DrugCom ID Component Drug Indication REF
1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole + Atenolol DCUHS7M 1-((2-chlorophenyl)diphenylmethyl)-1H-pyrazole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Acetohexamide + Atenolol DCDX1RB Acetohexamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Artemisinin + Atenolol DCW6TC7 Artemisinin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Clindamycin DCUAZGM Clindamycin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Diethylcarbamazine DC44RKY Diethylcarbamazine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Triamterene DCD65RT Triamterene Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Miglustat DCDSDFJ Miglustat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Triapine DC3E6XT Triapine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Acitretin DCNIUZL Acitretin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Pepstatin DCJH4LT Pepstatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Pamidronate DCFYM3F Pamidronate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Metyrosine DCBX901 Metyrosine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Emetine DCJO6C1 Emetine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Chlorzoxazone DCLDQG1 Chlorzoxazone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Docetaxel DC12MNJ Docetaxel Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Mecamylamine DCGTQD1 Mecamylamine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Arfolitixorin DCX7AB7 Arfolitixorin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + PF-02545920 DCI7SA1 PF-02545920 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Norcisapride DC31IBR Norcisapride Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Tiagabine DCTSTC7 Tiagabine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Imatinib DC5CT5E Imatinib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Darunavir DC4RR8L Darunavir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Methylene blue DC7GG9B Methylene blue Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Brincidofovir DCVRPZC Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Iloprost DCMB9I7 Iloprost Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Sumatriptan DCT7Y6H Sumatriptan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Cerivastatin DC7ZDM2 Cerivastatin Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Atenolol + Aciclovir DCS21IQ Aciclovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Bortezomib + Atenolol DC5CTSE Bortezomib Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Brincidofovir + Atenolol DCVPSNV Brincidofovir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Dextromethorphan + Atenolol DCH17DU Dextromethorphan Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Estramustine + Atenolol DC8K3YP Estramustine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ethambutol + Atenolol DCQRBGB Ethambutol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ethinyl estradiol + Atenolol DCN59FV Ethinyl estradiol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Fomepizole + Atenolol DC69382 Fomepizole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Guanfacine + Atenolol DCW3FD9 Guanfacine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
IT-141 + Atenolol DCSXKMA IT-141 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Lacosamide + Atenolol DC2YF8W Lacosamide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Leflunomide + Atenolol DCLW76J Leflunomide Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Maprotiline + Atenolol DC13ILI Maprotiline Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Memantine + Atenolol DCJSWYT Memantine Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Methotrexate + Atenolol DC6ZEZS Methotrexate Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Mycophenolic acid + Atenolol DCGHIJ0 Mycophenolic acid Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Oseltamivir + Atenolol DCDH9VG Oseltamivir Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
PMID28870136-Compound-43 + Atenolol DCABU3Y PMID28870136-Compound-43 Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Pramipexole + Atenolol DC2NXIZ Pramipexole Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Ramelteon + Atenolol DCTICVI Ramelteon Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Terameprocol + Atenolol DCFVAJ2 Terameprocol Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Testolactone + Atenolol DCXG487 Testolactone Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
Vorinostat + Atenolol DC9I2EG Vorinostat Chronic myelogenous leukemia (Cell Line: KBM-7) [3]
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⏷ Show the Full List of 50 DrugCom(s)
8 Clinical Trial Drug Combination(s) Consisting of This drug
DrugCom Name DrugCom ID Component Drug Indication REF
Aliskiren + Atenolol DC3NG06 Aliskiren Marfan Syndrome [4]
Ivabradine + Atenolol DCV2NUG Ivabradine Mitral Stenosis [5]
Labetalol + Atenolol DC5BEWA Labetalol Systolic Hypertension [6]
Labetalol + Atenolol DCFSHSV Labetalol Obesity, Morbid [7]
Amlodipine + Atenolol DCT5GO7 Amlodipine Cerebral Small Vessel Diseases [8]
Atenolol + Atenolol DCW74C2 Atenolol Essential Hypertension [9]
Valsartan + Atenolol DC82630 Valsartan Hypertension [10]
Bisoprolol + Atenolol DCROI8S Bisoprolol Hypertension [11]
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⏷ Show the Full List of 8 DrugCom(s)

References

1 Atenolol FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 548).
3 Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.
4 ClinicalTrials.gov (NCT01715207) Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFS
5 ClinicalTrials.gov (NCT01022463) Effect of Ivabradine on Heart Rate & Effort Tolerance in Mitral Stenosis in Sinus Rhythm
6 ClinicalTrials.gov (NCT04755764) Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy
7 ClinicalTrials.gov (NCT03105661) Use of Impedance Cardiography to Decrease the Risk of Pre-eclampsia in Obese Patients
8 ClinicalTrials.gov (NCT03082014) Effects of Amlodipine and Other Blood Pressure Lowering Agents on Microvascular Function
9 ClinicalTrials.gov (NCT00185185) Olmesartan Medoxomil in Atherosclerosis
10 ClinicalTrials.gov (NCT00396656) Safety and Efficacy of Valsartan vs Atenolol and Hydrochlorothiazide Combination on Blood Flow in Hypertensive Patients
11 ClinicalTrials.gov (NCT01939509) Hemodynamic Changes of Patients Receiving Atenolol/Bisoprolol