Details of the Drug Combinations

General Information of This Drug (ID: DMVEK07)

Drug Name

Magnesium Sulfate DMVEK07

Synonyms

Magnesiumsulfat; Bitter salt; Epsom salt; Hair salt; Heptahydrate Magnesium Sulfate; Kieserite [as monohydrate]; Magnesium Sulfate In Plastic Container; Magnesium Sulphate Hydrate; Magnesium bisulfate; Magnesium hydrogensulphate; Magnesium sulfate anhydrous; Magnesium sulfate dried; Magnesium sulfate hexahydrate; Magnesium sulfate solution; Magnesium sulphate; Sal Angalis; Sal De sedlitz; Sal amarum; Sal anglicum; Sal catharticum; Sal seidlitense; Salts of england; Sulfuric acid magnesium salt; Tomix OT; MgSO4; Epsom Sa (TN); Magnesium Sulfate, Heptahydrate; Magnesium sulfate in dextrose 5% in plastic container; Magnesium(II) sulfate; OT-S; Sel d'angleterre; Sulfate, Magnesium; Sulfuric acid magnesium salt (VAN); Sulfuric acid, magnesium salt; Magnesium sulfate (1:1); Magnesium(2+) ion sulfate; OT-S (drying agent); SDA 15-062-07; Sulfuric acid magnesium salt (1:1); Sulfuric acid, C10-16 alkyl ester, magnesium salt; Sulfuric acid, magnesium salt (1:1); Sulfuric acid, mono-C10-16-alkyl esters, magnesium salts; (C10-C16) Alkylalcohol sulfuric acid, magnesium salt

Indication

Disease Entry	ICD 11	Status	REF
Acute pain	MG31	Approved	[1]
Familial primary hypomagnesemia	N.A.	Approved	[2]
Hypertension, pregnancy-induced	N.A.	Approved	[2]
Mild pre-eclampsia	N.A.	Approved	[2]
Non-arteritic anterior ischemic optic neuropathy	9C40.40	Approved	[2]
Pain	MG30-MG3Z	Approved	[2]
Severe pre-eclampsia	N.A.	Approved	[2]
Traumatic brain injury	NA07.Z	Approved	[2]
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Therapeutic Class

Analgesics

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

List of Combinatorial Drugs (CBD) Containing This Drug

14 Clinical Trial Drug Combination(s) Consisting of This drug

DrugCom Name	DrugCom ID	Component Drug	Indication	REF
Lidocaine + Magnesium Sulfate	DC48UEU	Lidocaine	General Anesthesia	[3]
Methyldopa + Magnesium Sulfate	DC2ETS3	Methyldopa	Pre-eclampsia	[4]
Nifedipine + Magnesium Sulfate	DCHPN8O	Nifedipine	Threatened Preterm Labor	[5]
Oxytocin + Magnesium Sulfate	DCB1LU4	Oxytocin	Postpartum Hemorrhage	[6]
Cisatracurium + Magnesium Sulfate	DCDJF22	Cisatracurium	Muscle Relaxation	[7]
Diclofenac + Magnesium Sulfate	DCXDC8F	Diclofenac	Renal Colic	[8]
Levobupivacaine + Magnesium Sulfate	DCEKPM8	Levobupivacaine	Analgesia	[9]
Magnesium Sulfate + Rocuronium	DCBNL1Z	Rocuronium	Muscle Relaxation	[10]
Propofol + Magnesium Sulfate	DCESK2S	Propofol	Conscious Sedation	[11]
Dexamethasone + Magnesium Sulfate	DCHEBQF	Dexamethasone	Pain, Postoperative	[12]
Magnesium Sulfate + Midazolam	DC2TFOG	Midazolam	TBI (Traumatic Brain Injury)	[13]
Oxaliplatin + Magnesium Sulfate	DCGYPD4	Oxaliplatin	Chemotherapeutic Agent Toxicity	[14]
Cisatracurium + Magnesium Sulfate	DCFSCKA	Cisatracurium	Neuromuscular Block	[15]
Levosimendan + Magnesium Sulfate	DCBAYGS	Levosimendan	Aortic Coarctation	[16]
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References

1	Emerging drugs for acute ischemic stroke. Expert Opin Emerg Drugs. 2009 Mar;14(1):33-42.
2	Magnesium Sulfate FDA Label
3	ClinicalTrials.gov (NCT01342510) Combination of Magnesium and Lidocaine for the Pretreatment of Pain That is Caused by the Injection of Propofol
4	ClinicalTrials.gov (NCT01911494) Community Level Interventions for Pre-eclampsia
5	ClinicalTrials.gov (NCT05345132) Nifedipine Plus Magnesium Sulfate Versus Magnesium Sulfate for Very Early Preterm Tocolysifs
6	ClinicalTrials.gov (NCT02647268) Effect of Magnesium Sulphate Pre-exposure on Oxytocin-induced Contractility in Desensitized Human Myometrium - an in Vitro Study
7	ClinicalTrials.gov (NCT05736744) Effect of Magnesium Sulphate Pretreatment in Pediatric Laparoscopy
8	ClinicalTrials.gov (NCT03199924) Treatment of Renal Colic in the Emergency Departement (ED).
9	ClinicalTrials.gov (NCT04275661) Ketamine Versus Magnesium Sulphate as Adjuvants for ESPB in Breast Cancer Surgery
10	ClinicalTrials.gov (NCT02669368) Magnesium Sulfate Effects on Onset and Duration of Low Dose Rocuronium in Patients Undergoing Laparoscopic Cholecystectomy
11	ClinicalTrials.gov (NCT03548493) Magnesium Sulphate Versus Fentanyl for Conscious Sedation in CSDH
12	ClinicalTrials.gov (NCT03643666) Intraperitoneal Dexamethasone vs Dexamethasone Plus Magnesium Sulphate for Pain Relief in Laparoscopic Cholecystectomy
13	ClinicalTrials.gov (NCT05340803) Sedation of Ventilated Traumatic Brain Injury Patients With Midazolam Alone Versus Combination With Dexmedetomidine or Magnesium Sulfate; Monitored by Ultrasonograghic Optic Nerve Sheath Diameter
14	ClinicalTrials.gov (NCT01099449) Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy
15	ClinicalTrials.gov (NCT02483611) Effects of Intravenous Lidocaine Associated With Magnesium Sulfate on the Cisatracurium-Induced Neuromuscular Block
16	ClinicalTrials.gov (NCT04330755) Levosimendan Versus Combination With Magnesium Sulphate on Spine Protection by NIRS in Infants Undergoing Coarctectomy