Details of the Drug Formulations

General Information of Drug (ID: DMP1I6Y)

Drug Name
Alectinib Drug Info
Synonyms
1256580-46-7; CH5424802; CH 5424802; AF-802; Alecensa; UNII-LIJ4CT1Z3Y; AF 802; LIJ4CT1Z3Y; Alectinib (CH5424802); 9-ethyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile; CHEMBL1738797; AF802; 9-Ethyl-6,6-Dimethyl-8-[4-(Morpholin-4-Yl)piperidin-1-Yl]-11-Oxo-6,11-Dihydro-5h-Benzo[b]carbazole-3-Carbonitrile; 9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile; AK170451; C30H34N4O2; Alectinib; 9-ethyl-6,6-dimethyl-
Indication
Disease Entry ICD 11 Status REF
Lung cancer 2C25.0 Approved [1]
Non-small-cell lung cancer 2C25.Y Phase 2 [2]
Cross-matching ID
PubChem CID
49806720
ChEBI ID
CHEBI:90936
CAS Number
1256580-46-7
TTD ID
D0U3SY
INTEDE ID
DR0059
ACDINA ID
D00016

Full List of Drug Formulations Containing This Drug

Alectinib 150 mg capsule
Company Formulation ID FDA Description
Genentech F00604 Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 2; Magnesium stearate; Potassium chloride; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Aluminum oxide; Carboxymethylcellulose calcium; Carnauba wax; Carrageenan; Glyceryl oleate; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Shellac; Starch, corn
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Alectinib Hydrochloride eq 150mg base capsule
Company Formulation ID FDA Description
Hoffmann-La Roche F23327 Lactose Monohydrate; Hydroxypropylcellulose; Sodium Lauryl Sulfate; Magnesium Stearate; Carboxymethylcellulose Calcium; Hypromellose; Carrageenan; Potassium Chloride; Titanium Dioxide; Corn Starch; Carnauba Wax; Red Iron Oxide (E172); Yellow Iron Oxide (E172); Fd&C Blue No. 2 Aluminum Lake (E132); Carnauba Wax; White Shellac; Glyceryl Monooleate
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References

1 Alectinib versus crizotinib in patients with ALK-positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial. Lancet. 2017 Jul 1;390(10089):29-39.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7739).