Details of the Drug-Related molecule(s) Activity Atlas

General Information of Drug (ID: DMFZXI2)

• Drug Name: NVP-TAE684 Drug Info
• Synonyms: 761439-42-3; NVP-TAE684; NVP-TAE 684; TAE684; TAE-684; 5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine; TAE684 (NVP-TAE684); TAE 684; UNII-EH1713MN4K; CHEMBL509032; EH1713MN4K; 5-Chloro-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine; C30H40ClN7O3S
• Cross-matching ID:
  PubChem CID: 16038120
  ChEBI ID: CHEMBL509032
  CAS Number: CAS 761439-42-3
  TTD ID: D0R2WK

Molecule-level Activity Landscape of This Drug

IC50 (44) EC50 (7) Kd (433) Ki (181) Download

Molecule Name	Gene Name	UniProt ID	Type	IC50 (nM)	Details
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Molecule Name	Gene Name	UniProt ID	Type	EC50 (nM)	Details
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Molecule Name	Gene Name	UniProt ID	Type	Kd (nM)	Details
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Molecule Name	Gene Name	UniProt ID	Type	Ki (nM)	Details
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Experimental Drug Sensitivity Data Across Cancer Cell Lines

Cell Line	Related Disease	IC50 (Log₂ µM)	Original Dataset	Details
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Cytotoxic Activity Landscape of This Drug

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Cell Line	Disease	Value (nM)	ChEMBL Assay ID	Details
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