Details of the Drug-Related molecule(s) Activity Atlas

General Information of Drug (ID: DMMX75K)

• Drug Name: LEE011 Drug Info
• Synonyms: Ribociclib; LEE011; 1211441-98-3; LEE-011; Kisqali; Ribociclib(LEE011); UNII-TK8ERE8P56; LEE 011; 7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; TK8ERE8P56; Ribociclib (LEE011); AK174906; 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7H-pyrrolo [2,3-d]pyrimidine-6-carboxylic acid dimethylamide; Ribociclib [USAN:INN]; LEE011A; Tube013
• Cross-matching ID:
  PubChem CID: 44631912
  ChEBI ID: CHEMBL3545110
  CAS Number: CAS 1211441-98-3
  TTD ID: D08MXP

Molecule-level Activity Landscape of This Drug

IC50 (7) Kd (8) Download

Molecule Name	Gene Name	UniProt ID	Type	IC50 (nM)	Details
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Molecule Name	Gene Name	UniProt ID	Type	Kd (nM)	Details
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Experimental Drug Sensitivity Data Across Cancer Cell Lines

Cell Line	Related Disease	IC50 (Log₂ µM)	Original Dataset	Details
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Cytotoxic Activity Landscape of This Drug

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Cell Line	Disease	Value (nM)	ChEMBL Assay ID	Details
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