Details of the Drug-Related molecule(s) Activity Atlas

General Information of Drug (ID: DMTI8YE)

Drug Name
Bosutinib Drug Info
Synonyms
SKI 606; SKI606; Bosutinib (USAN); PF-5208763; SKI-606; Xy]-3-quinolinecarbonitrile; 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile; 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile; 4-(2,4-dichloro-5-methoxyanilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile; 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propo; 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile; Bosutinib (BCR-ABL inhibitor 3rd gen)
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
5328940
ChEBI ID
CHEMBL288441
CAS Number
CAS 380843-75-4
TTD ID
D0OB0F
VARIDT Drug ID
DR00253
INTEDE Drug ID
DR0224
ACDINA Drug ID
D00075

Molecule-level Activity Landscape of This Drug
Molecule Name Gene Name UniProt ID Type IC50 (nM) Details
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Molecule Name Gene Name UniProt ID Type Kd (nM) Details
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Molecule Name Gene Name UniProt ID Type Ki (nM) Details
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Experimental Drug Sensitivity Data Across Cancer Cell Lines
Cell Line Related Disease IC50 (Log₂ µM) Original Dataset Details
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Cytotoxic Activity Landscape of This Drug

Cell Line Disease Value (nM) ChEMBL Assay ID Details
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