Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DM1Y2JH)

Drug Name

Inulin Drug Info

Synonyms

Inulin [BAN]; Inulin and sodium chloride; Inulin from Jerusalem artichokes; Inulin USP 27

Indication

Disease Entry	ICD 11	Status	REF
Measure kidney function	MG02	Approved	[1]

Therapeutic Class

Hypoglycemic Agents

Cross-matching ID

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	Highest Status	REF
Beta-fructofuranosidase (BFRU)	DE4EX78	A0A173R035_9FIRM	Approved	[3]

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The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Insulin (INS)	DTT	INS	0.848	2.138	0.379	0.926

Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease

Measure kidney function

ICD Disease Classification

MG02

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Insulin (INS)	DTT	INS	6.70E-01	-0.12	-0.46

Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1	Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77.
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
3	Substrate-driven gene expression in Roseburia inulinivorans: importance of inducible enzymes in the utilization of inulin and starch. Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4672-9.