Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMEYHG9)

Drug Name
Elotuzumab Drug Info
Synonyms BMS-901608
Indication
Disease Entry ICD 11 Status REF
Multiple myeloma 2A83 Approved [1]
Cross-matching ID
TTD Drug ID
DMEYHG9

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
SLAM family member 7 SLAMF7 (CS1) TT7ILZ1 SLAF7_HUMAN Not Available [2]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
SLAM family member 7 SLAMF7 (CS1) DTT SLAMF7 3.17 4.178 3.17 3.678
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

ICD Disease Classification 02 Neoplasm
Disease Class ICD-11: 2C82 Prostate cancer
The Studied Tissue Bone marrow
The Studied Disease Multiple myeloma [ICD-11:2C82]
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
SLAM family member 7 SLAMF7 (CS1) DTT SLAMF7 9.74E-01 0.13 0.31
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8361).
2 Market watch: Upcoming catalysts in Q2 2015. Nat Rev Drug Discov. 2015 Apr;14(4):228.