Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMG7PC0)

• Drug Name: Anti-D Drug Info
• Synonyms: (2-Amino-D-glucose Hydrochloride); glu-cosamine hydrochloride; 3h-glucosamine hydrochloride; SCHEMBL21212; SPECTRUM1500316; MolPort-003-666-196; Pharmakon1600-01500316; HMS1920B13; NSC757051; CCG-39600

Indication

Disease Entry	ICD 11	Status	REF
Idiopathic thrombocytopenic purpura	3B64.10	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 9859210
  CAS Number: CAS 66-84-2
  TTD Drug ID: DMG7PC0

Molecule(s) Related to This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Dopamine D2 receptor (D2R)	TTEX248	DRD2_HUMAN	Antagonist	[1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule	Molecule Type	Gene Name	Liver	Colon	Kidney	Small Intestine
Dopamine D2 receptor (D2R)	DTT	DRD2	5.345	5.634	5.789	5.901

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

• The Studied Disease: Idiopathic thrombocytopenic purpura
• ICD Disease Classification: 3B64.10

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Dopamine D2 receptor (D2R)	DTT	DRD2	2.50E-02	-0.08	-0.49

References

• [1] Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54.