Details of the Drug

General Information of Drug (ID: DMG7PC0)

Drug Name
Anti-D
Synonyms
(2-Amino-D-glucose Hydrochloride); glu-cosamine hydrochloride; 3h-glucosamine hydrochloride; SCHEMBL21212; SPECTRUM1500316; MolPort-003-666-196; Pharmakon1600-01500316; HMS1920B13; NSC757051; CCG-39600
Indication
Disease Entry ICD 11 Status REF
Idiopathic thrombocytopenic purpura 3B64.10 Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski):
1		 Molecular Weight 215.63
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 1
Hydrogen Bond Donor Count 6
Hydrogen Bond Acceptor Count 6
Chemical Identifiers
Formula
C6H14ClNO5
IUPAC Name
(2R,3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol;hydrochloride
Canonical SMILES
C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)N)O)O)O.Cl
InChI
InChI=1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6-;/m1./s1
InChIKey
QKPLRMLTKYXDST-OCOFDJSDSA-N
Cross-matching ID
PubChem CID
9859210
CAS Number
66-84-2
TTD ID
D0J2NS
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Dopamine D2 receptor (D2R) TTEX248 DRD2_HUMAN Antagonist [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Idiopathic thrombocytopenic purpura
ICD Disease Classification 3B64.10
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Dopamine D2 receptor (D2R) DTT DRD2 2.50E-02 -0.08 -0.49
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54.