Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMVL57U)

Drug Name
US9388139, 12 Drug Info
Synonyms SCHEMBL12493454; CHEMBL3899621; BDBM236643; US9388139, 12
Cross-matching ID
PubChem CID
60194756
TTD Drug ID
DMVL57U

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phosphodiesterase 3B (PDE3B) TTN34SQ PDE3B_HUMAN Inhibitor [1]

The Expression Level of Molecule(s) in Normal Tissue of Major ADME-Related Organs

Molecule Molecule Type Gene Name Liver Colon Kidney Small Intestine
Phosphodiesterase 3B (PDE3B) DTT PDE3B 6.414 6.131 4.591 5.184
Molecule Expression Atlas in Normal Tissue of Major ADME-related organs

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Phosphodiesterase 3B (PDE3B) DTT PDE3B 9.09E-01 0.1 0.35
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Derivatives of celeboxib, use thereof and preparation thereof. US9388139.