Details of the Drug-Related molecule(s) Expression Atlas

General Information of Drug (ID: DMZMQDN)

Drug Name
NK-1001 Drug Info
Synonyms NNYK-1001; NYK-1001
Indication
Disease Entry ICD 11 Status REF
Atrial fibrillation BC81.3 Discontinued in Phase 2 [1]
Cross-matching ID
PubChem CID
3040841
CAS Number
CAS 53025-93-7
TTD Drug ID
DMZMQDN

Molecule(s) Related to This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Heat shock protein 27 (HSP27) TTMG98T HSPB3_HUMAN Modulator [2]
Heat shock protein 70 (HSP70) TTHYBIX HS71A_HUMAN; HS71B_HUMAN Modulator [2]

The Expression Level of Molecule(s) between Disease Section and Healthy Individual Tissue

The Studied Disease Atrial fibrillation
ICD Disease Classification BC81.3
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Heat shock protein 70 (HSP70) DTT HSPA1A; HSPA1B 1.03E-20 0.32 1.2
Molecular Expression Atlas between Disease Section and Healthy Individual Tissue

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033456)
2 Novel therapeutic targets in the management of atrial fibrillation. Am J Cardiovasc Drugs. 2014 Dec;14(6):403-21.