Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0O8N6)

Drug Name

Propionate Drug Info

Synonyms

propanoate; Propanoic acid, ion(1-); propanate; EtCO2 anion; UNII-AKW5EM890C; AKW5EM890C; pseudoacetate; metacetonate; ethanecarboxylate; 1972/3/7; 28488-34-8; CHEMBL500826; NCGC00159468-02; Bugle; Propionate ion; carboxylatoethane; AC1L2XEZ; Sentry Grain Preservative; AC1Q2RL9; CH3-CH2-COO(-); CHEBI:17272; CTK4G1579; DTXSID90222279; XBDQKXXYIPTUBI-UHFFFAOYSA-M; BDBM50257201; STL483862; AKOS015901051; NCGC00159468-03; NCGC00159468-04; CJ-04452; ZB014971; Propanoic acid,neodymium(3+) salt (9CI); LS-190254; 3002-EP2374454A1

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 104745
ChEBI ID: CHEBI:17272
CAS Number: CAS 72-03-7
TTD Drug ID: DM0O8N6
VARIDT Drug ID: DR00156

Molecule-Related Drug Atlas

Molecule Type:

DTT

DTP

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Mycobacterium Biosynthetic alanine racemase (MycB alr)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cycloserine	DMT1I52	Bacterial infection	1A00-1C4Z	Approved	[3]
Acetate Ion	DMD08RH	Discovery agent	N.A.	Investigative	[3]
Pyridoxamine-5'-Phosphate	DMQ6POC	Discovery agent	N.A.	Investigative	[3]
Lysine Nz-Carboxylic Acid	DMW1YK3	Discovery agent	N.A.	Investigative	[3]
Pyridoxyl-N,O-Cycloserylamide-5-Monophosphate	DM7AW0X	Discovery agent	N.A.	Investigative	[3]
N-(5'-Phosphopyridoxyl)-D-Alanine	DM3FCAI	Discovery agent	N.A.	Investigative	[3]
Pyridoxyl-Alanine-5-Phosphate	DMUVCWY	Discovery agent	N.A.	Investigative	[3]
Propanoic Acid	DM9TN2W	Discovery agent	N.A.	Investigative	[3]
3-fluorovinylglycine	DMECBLA	Discovery agent	N.A.	Investigative	[4]
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⏷ Show the Full List of 9 Drug(s)

Drug(s) Transported By Sodium-coupled monocarboxylate transporter 1 (SLC5A8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Gabapentin enacarbil	DMJY2TM	Postherpetic neuralgia	1E91.5	Phase 2	[5]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Mycobacterium Biosynthetic alanine racemase (MycB alr)	TT6TMZU	ALR_MYCSM	Inhibitor	[1]

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Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
Sodium-coupled monocarboxylate transporter 1 (SLC5A8)	DTE3TAW	SC5A8_HUMAN	Substrate	[2]

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References

1	Molecular dynamics studies of alanine racemase: a structural model for drug design. Biopolymers. 2003 Oct;70(2):186-200.
2	SLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanisms. Biochem J. 2016 May 1;473(9):1113-24.
3	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
4	Mechanism-based inactivation of alanine racemase by 3-halovinylglycines. J Biol Chem. 1991 Nov 15;266(32):21657-65.
5	Clinical pharmacokinetic drug interaction studies of gabapentin enacarbil, a novel transported prodrug of gabapentin, with naproxen and cimetidine. Br J Clin Pharmacol. 2010 May;69(5):498-507.