Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM0YD3Z)

Drug Name
US8598172, 1 Drug Info
Synonyms SCHEMBL1527199; CHEMBL3660143; BDBM108214; US8598172, 1
Cross-matching ID
PubChem CID
42611166
TTD Drug ID
DM0YD3Z

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Polo-like kinase 2 (PLK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ON-123 DMHLEGT Solid tumour/cancer 2A00-2F9Z Investigative [2]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Polo-like kinase 2 (PLK2) TT976FS PLK2_HUMAN Inhibitor [1]

References

1 Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors. US8598172.
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2169).