Details of the Drug

General Information of Drug (ID: DMHLEGT)

Drug Name

ON-123

Synonyms

ON-1231320; ON-123 series (cancer); Sulfonyl pyridopyrimidines (cancer), Onconova; ON-123 series (cancer), Onconova; Plk-2 inhibitors (cancer), Onconova; Polo-like kinase 2 inhibitors (cancer), Onconova

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Investigative	[1]
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Cross-matching ID

TTD ID: D02IZN

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Polo-like kinase 2 (PLK2)	TT976FS	PLK2_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2169).