Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM3M652)

Drug Name

Daio-Orengedokuto (DOT) Drug Info

Synonyms

26159-34-2; Miranax; Naproxen sodium salt; Synflex; Naprodol; Naprodil; Leniartril; Gibixen; Floxalin; Flogogin; Aprowell; Anapran; Primeral; Pactens; Naprovite; Gibinap; Floneks; Anaprotab; Monarit; Karoksen; Sodimax; Natrioxen; Floginex; Opraks; Kapnax; Tandax; Flogen; Nixal; Aprol; Naprux Gesic; Causalon Pro; Naproxen natrium; Axer Alfa; Dysmenalgit; Veradol; Naprium; Diocodal; Proxen; Prexan; Naprux; A-Nox; Xenar; Laser; Apo-Napro-NA; UNII-9TN87S3A3C; sodium na

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 23681059
ChEBI ID: CHEBI:7477
CAS Number: CAS 26159-34-2
TTD Drug ID: DM3M652

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Pancreatic triacylglycerol lipase (PNLIP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Orlistat	DMRJSP8	Obesity	5B81	Approved	[2]
Dalbavancin	DMGMNH3	Bacterial infection	1A00-1C4Z	Approved	[3]
Pancrecarb	DMOML9Q	Pancreatic malfunction	DC30-DC3Z	NDA filed	[4]
Liprotamase	DMNF4UH	Cystic fibrosis	CA25	Phase 3	[5]
MS-1819	DM35YFC	Exocrine pancreatic insufficiency	DC35.1	Phase 1/2	[6]
AZM-131	DMLCSRF	Obesity	5B81	Terminated	[7]
B-Octylglucoside	DMMO75G	Discovery agent	N.A.	Investigative	[8]
(Hydroxyethyloxy)Tri(Ethyloxy)Octane	DMY6FUD	Discovery agent	N.A.	Investigative	[8]
B-Nonylglucoside	DM48VJR	Discovery agent	N.A.	Investigative	[9]
METHOXYUNDECYLPHOSPHINIC ACID	DMY0O7X	Discovery agent	N.A.	Investigative	[9]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Pancreatic triacylglycerol lipase (PNLIP)	TTXMY0J	LIPP_HUMAN	Inhibitor	[1]

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References

1	Daio-Orengedokuto inhibits HMG-CoA reductase and pancreatic lipase. Biol Pharm Bull. 2002 Nov;25(11):1442-5.
2	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
3	Pfizer. Product Development Pipeline. March 31 2009.
4	Clinical pipeline report, company report or official report of Digestive Care.
5	Clinical pipeline report, company report or official report of Anthera Pharmaceuticals.
6	Clinical pipeline report, company report or official report of AzurRx.
7	US patent application no. 7217,697, Glucopyranosyloxypyrazole derivative medicinal composition containing the same medicinal use thereof and intermediate therefor.
8	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
9	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.