Details of the Drug

General Information of Drug (ID: DM3M652)

• Drug Name: Daio-Orengedokuto (DOT)
• Synonyms: 26159-34-2; Miranax; Naproxen sodium salt; Synflex; Naprodol; Naprodil; Leniartril; Gibixen; Floxalin; Flogogin; Aprowell; Anapran; Primeral; Pactens; Naprovite; Gibinap; Floneks; Anaprotab; Monarit; Karoksen; Sodimax; Natrioxen; Floginex; Opraks; Kapnax; Tandax; Flogen; Nixal; Aprol; Naprux Gesic; Causalon Pro; Naproxen natrium; Axer Alfa; Dysmenalgit; Veradol; Naprium; Diocodal; Proxen; Prexan; Naprux; A-Nox; Xenar; Laser; Apo-Napro-NA; UNII-9TN87S3A3C; sodium na

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight; 252.24
  Logarithm of the Partition Coefficient; Not Available
  Rotatable Bond Count; 3
  Hydrogen Bond Donor Count; 0
  Hydrogen Bond Acceptor Count; 3
• Chemical Identifiers:
  Formula: C14H13NaO3
  IUPAC Name: sodium;(2S)-2-(6-methoxynaphthalen-2-yl)propanoate
  Canonical SMILES: C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)[O-].[Na+]
  InChI: InChI=1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1
  InChIKey: CDBRNDSHEYLDJV-FVGYRXGTSA-M
• Cross-matching ID:
  PubChem CID: 23681059
  ChEBI ID: CHEMBL7477
  CAS Number: 26159-34-2
  TTD ID: D09CGL
• Drug ADMET Endpoint Profile (DAE)NEW: Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Pancreatic triacylglycerol lipase (PNLIP)	TTXMY0J	LIPP_HUMAN	Inhibitor	[1]

References

• [1] Daio-Orengedokuto inhibits HMG-CoA reductase and pancreatic lipase. Biol Pharm Bull. 2002 Nov;25(11):1442-5.