Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM4H78P)

Drug Name

NT-501 Drug Info

Synonyms

NTC-201E; CNTF cell implant (ECT), Neurotech; CNTF ophthalmic cell implant (retinitis pigmentosa), Neurotech; Cell implant (ciliary neurotrophic factor), Neurotech; Cell implant (retinitis pigmentosa, ECT), Neurotech

Indication

Disease Entry	ICD 11	Status	REF
Ocular inflammation	9C61.24	Phase 2/3	[1]
Retinitis pigmentosa	9B70	Phase 2/3	[2]
Macular telangiectasia type 2	9B75.3	Phase 2	[2]

Cross-matching ID

TTD Drug ID: DM4H78P

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Clinical Trial Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Ciliary neurotrophic factor receptor alpha (CNTFR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
PegCNTF	DMW7VGZ	Obesity	5B81	Phase 1	[4]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Ciliary neurotrophic factor receptor alpha (CNTFR)	TTT2F9E	CNTFR_HUMAN	Modulator	[3]

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References

1	ClinicalTrials.gov (NCT00447980) A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis Pigmentosa. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	Clinical pipeline report, company report or official report of Neurotech.
4	Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.