Details of the Drug

General Information of Drug (ID: DM4H78P)

Drug Name

NT-501

Synonyms

NTC-201E; CNTF cell implant (ECT), Neurotech; CNTF ophthalmic cell implant (retinitis pigmentosa), Neurotech; Cell implant (ciliary neurotrophic factor), Neurotech; Cell implant (retinitis pigmentosa, ECT), Neurotech

Indication

Disease Entry	ICD 11	Status	REF
Ocular inflammation	9C61.24	Phase 2/3	[1]
Retinitis pigmentosa	9B70	Phase 2/3	[2]
Macular telangiectasia type 2	9B75.3	Phase 2	[2]
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Cross-matching ID

TTD ID: D0A7WO

Repurposed Drugs (RPD)

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Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Ciliary neurotrophic factor receptor alpha (CNTFR)	TTT2F9E	CNTFR_HUMAN	Modulator	[3]

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Molecular Interaction Atlas (MIA)

MIA Detail

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References

1	ClinicalTrials.gov (NCT00447980) A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis Pigmentosa. U.S. National Institutes of Health.
2	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3	Clinical pipeline report, company report or official report of Neurotech.