Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM5ZQK1)

• Drug Name: 4-Hydroxy-pent-2-enoic acid Drug Info
• Synonyms: CHEMBL171595; (E)-4-hydroxypent-2-enoic acid; YANJKPZKTWMMOF-NSCUHMNNSA-N; 4-Hydroxy-pent-2-enoic acid; trans-4-hydroxypent-2-enoic acid; AC1NSI5H; 4-hydroxy-2-pentenoic acid; SCHEMBL166635; 2-Pentenoic acid, 4-hydroxy-; BDBM50023574; (2E)-4-Hydroxy-2-pentenoic acid #; AKOS022632862

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 5363658
  TTD Drug ID: DM5ZQK1
  VARIDT Drug ID: DR01079

Molecule-Related Drug Atlas

Drug(s) Targeting Gamma-hydroxybutyrate receptor (SLC52A2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
4-Hydroxy-3-methyl-butyric acid	DM6AHO4	Discovery agent	N.A.	Investigative	[1]
4-Hydroxy-4-phenyl-butyric acid	DMDWGS9	Discovery agent	N.A.	Investigative	[1]
4-hydroxy-but-2-enoate	DMCA2XQ	Discovery agent	N.A.	Investigative	[1]
5-hydroxy-pentanoate	DMJQFZH	Discovery agent	N.A.	Investigative	[1]
4-Hydroxy-4-phenyl-but-2-enoic acid	DMIVQGW	Discovery agent	N.A.	Investigative	[1]
4-Hydroxy-3-methyl-but-2-enoic acid	DMWDBHC	Discovery agent	N.A.	Investigative	[1]
4-Hydroxy-pentanoic acid	DMDGKFV	Discovery agent	N.A.	Investigative	[1]
4-Cyclohexyl-4-hydroxy-but-2-enoic acid	DMTFL5J	Discovery agent	N.A.	Investigative	[1]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Gamma-hydroxybutyrate receptor (SLC52A2)	TT6TKEN	S52A2_HUMAN	Inhibitor	[1]

References

• [1] Analogues of gamma-hydroxybutyric acid. Synthesis and binding studies. J Med Chem. 1988 May;31(5):893-7.