Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM6EICU)

Drug Name

N-[O-Phosphono-Pyridoxyl]-Isoleucine Drug Info

Synonyms

ILP; AC1L9K3U; (3S)-2-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-3-methylpentanoic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Branched-chain-amino-acid transaminase 2 (BCAT2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Pyridoxamine-5'-Phosphate	DMQ6POC	Discovery agent	N.A.	Investigative	[1]
Alpha-ketoisovalerate	DMBZTS5	Discovery agent	N.A.	Investigative	[1]
N'-(phenylsulfonyl)benzofuran-2-carbohydrazide	DMJO3B1	Discovery agent	N.A.	Investigative	[2]
N'-(phenylsulfonyl)quinoline-6-carbohydrazide	DMQETUY	Discovery agent	N.A.	Investigative	[2]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Branched-chain-amino-acid transaminase 2 (BCAT2)	TTF9OQ6	BCAT2_HUMAN	Inhibitor	[1]

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References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
2	The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases. Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40.