Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM857X2)

• Drug Name: benzyl bromide Drug Info
• Synonyms: BENZYL BROMIDE; 100-39-0; (Bromomethyl)benzene; alpha-Bromotoluene; Bromophenylmethane; Benzene, (bromomethyl)-; Benzene, bromomethyl-; Phenylmethyl bromide; 1-Bromotoluene; benzylbromide; Cyclite; bromomethylbenzene; A-BROMOTOLUENE; Toluene, alpha-bromo-; BnBr; NSC 8041; UNII-XR75BS721D; HSDB 369; .alpha.-Bromotoluene; .omega.-Bromotoluene; CCRIS 5980; EINECS 249-248-3; EINECS 202-847-3; UN1737; Toluene, .alpha.-bromo-; ALPHA-BROMOPHENYLMETHANE; AI3-15300; XR75BS721D; CHEMBL1085946; CHEBI:59858; AGEZXYOZHKGVCM-UHFFFAOYSA-N

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Cross-matching ID:
  PubChem CID: 7498
  ChEBI ID: CHEMBL59858
  CAS Number: CAS 100-39-0
  TTD Drug ID: DM857X2

Molecule-Related Drug Atlas

Drug(s) Targeting Transformation-sensitive protein p120 (TRPA1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Menthol	DMG2KW7	Back pain	ME84.Z	Approved	[4]
LY3526318	DMFXNQM	Chronic low-back pain	MG30	Phase 2	[5]
HX-100	DMFRM15	Diabetic neuropathy	8C0Z	Phase 1	[6]
NPPB	DMFIWAN	Discovery agent	N.A.	Investigative	[7]
acetaldehyde	DMJFKG4	Discovery agent	N.A.	Investigative	[8]
[3H]resolvin D1	DMFT0HU	Discovery agent	N.A.	Investigative	[9]
Formaldehyde	DM7Q6M0	Discovery agent	N.A.	Investigative	[10]
icilin	DMYVOL9	Discovery agent	N.A.	Investigative	[11]
4-oxo-nonenal	DMPX1J9	Discovery agent	N.A.	Investigative	[12]
dibutyl phthalate	DMEDGKO	Discovery agent	N.A.	Investigative	[13]

Drug(s) Affected By Interleukin-8 (CXCL8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrocortisone	DMGEMB7	Acne vulgaris	ED80	Approved	[14]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[15]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[16]
Pantothenic acid	DM091H2	Vitamin deficiency	5B55-5B71	Approved	[17]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[18]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[19]
Fexofenadine	DM17ONX	Allergic rhinitis	CA08.0	Approved	[20]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[21]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[22]
Lumiracoxib	DM1S4AG	Chronic renal failure	GB61.Z	Approved	[20]

Drug(s) Affected By Tumor necrosis factor-inducible gene 6 protein (TNFAIP6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[23]
Selenium	DM25CGV	N. A.	N. A.	Approved	[24]
Clavulanate	DM2FGRT	Bacteremia	1A73	Approved	[20]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[25]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[26]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[27]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[20]
Nevirapine	DM6HX9B	Human immunodeficiency virus infection	1C62	Approved	[20]
Trihexyphenidyl	DMB19L8	Dystonia	8A02	Approved	[20]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[20]

Drug(s) Affected By Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[28]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[29]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[30]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[31]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[32]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[33]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[34]
Penicillamine	DM40EF6	Cystinuria	5C60.2	Approved	[35]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[36]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[37]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Transformation-sensitive protein p120 (TRPA1)	TTELV3W	TRPA1_HUMAN	Activator	[2]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Interleukin-8 (CXCL8)	OTS7T5VH	IL8_HUMAN	Gene/Protein Processing	[3]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)	OTXEE550	APR_HUMAN	Gene/Protein Processing	[3]
Tumor necrosis factor-inducible gene 6 protein (TNFAIP6)	OT1SLUZH	TSG6_HUMAN	Gene/Protein Processing	[3]

References

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